Transcription Factor

Accessions: P28357 (JASPAR 2024)
Names: Homeobox protein Hox-4.4, Homeobox protein Hox-5.2, Homeobox protein Hox-D9, HXD9_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 339
Pfam Domains: 1-113 Hox9 activation region
273-329 Homeobox domain
Sequence:
(in bold interface residues)
1 MSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGTQGRPAGVADGPAAATAEFASCSFAP 60
61 KSSVFSASWSAVAAQPPAAATMSGLYHPYVSPPPLAAAEPGRYVRSWMEPLPGFPGGAGG 120
121 GGGSGGGGGGGPGPVPSPGGPANGRHYGIKPETGAAPAPAAASTSSSSSTSSSSSSKRTE 180
181 CSAARESQGSGGPEFPCNSFLRDKAAAATGNGPGVGIGTGPGAVGSSEPSACSDHPSPGC 240
241 SLKEEEKQPPQPPQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRD 300
301 RRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD
Interface Residues: 256, 259, 260, 263, 273, 274, 275, 276, 314, 315, 317, 318, 321, 322, 325, 326, 329
3D-footprint Homologues: 5zfz_A, 1ig7_A, 6a8r_A, 2h1k_B, 1puf_A, 1fjl_B, 6m3d_C, 3cmy_A, 1nk2_P, 1zq3_P, 1jgg_B, 3lnq_A, 2lkx_A, 7q3o_C, 2ld5_A, 6es3_K, 2hdd_A, 1b72_A, 5zjt_E, 4cyc_A, 2r5y_A, 1puf_B, 7psx_B, 5hod_A, 2hos_A, 5jlw_D, 4xrs_G, 3a01_E, 3rkq_B, 5flv_I, 1le8_A, 2xsd_C, 1e3o_C, 7xrc_C, 1au7_A, 3d1n_M, 1du0_A, 4qtr_D, 1o4x_A, 1k61_B
Binding Motifs: MA0913.1 gymATwAAaw
Publications: Shanmugam K, Green NC, Rambaldi I, Saragovi HU, Featherstone MS. PBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteins. Mol Cell Biol 19:7577-88 (1999). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.