Transcription Factor

Accessions: Q60795 (JASPAR 2024)
Names: NF-E2-related factor 2, NF2L2_MOUSE, NFE2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear factor, erythroid derived 2, like 2
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 597
Pfam Domains: 491-534 bZIP transcription factor
494-533 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 MMDLELPPPGLQSQQDMDLIDILWRQDIDLGVSREVFDFSQRQKDYELEKQKKLEKERQE 60
61 QLQKEQEKAFFAQFQLDEETGEFLPIQPAQHIQTDTSGSASYSQVAHIPKQDALYFEDCM 120
121 QLLAETFPFVDDHESLALDIPSHAESSVFTAPHQAQSLNSSLEAAMTDLSSIEQDMEQVW 180
181 QELFSIPELQCLNTENKQLADTTAVPSPEATLTEMDSNYHFYSSISSLEKEVGNCGPHFL 240
241 HGFEDSFSSILSTDDASQLTSLDSNPTLNTDFGDEFYSAFIAEPSDGGSMPSSAAISQSL 300
301 SELLDGTIEGCDLSLCKAFNPKHAEGTMEFNDSDSGISLNTSPSRASPEHSVESSIYGDP 360
361 PPGFSDSEMEELDSAPGSVKQNGPKAQPAHSPGDTVQPLSPAQGHSAPMRESQCENTTKK 420
421 EVPVSPGHQKAPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVDDFNEMMSKE 480
481 QFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDR 540
541 NLHLLKRRLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDTKKN
Interface Residues: 495, 499, 500, 502, 503, 506, 507, 510
3D-footprint Homologues: 7x5e_F, 1skn_P, 2wt7_A, 7x5e_E, 2wt7_B, 5t01_B, 5vpe_D
Binding Motifs: MA0150.2 casmrTGACTCAGCA
MA0150.3 rTGACTCAGCA
Binding Sites: MA0150.2.1
MA0150.2.10
MA0150.2.11
MA0150.2.12
MA0150.2.13
MA0150.2.14
MA0150.2.15
MA0150.2.16
MA0150.2.17
MA0150.2.18
MA0150.2.19
MA0150.2.2
MA0150.2.20
MA0150.2.3
MA0150.2.4
MA0150.2.5
MA0150.2.6
MA0150.2.7
MA0150.2.8
MA0150.2.9
MA0150.3.1
MA0150.3.10
MA0150.3.11
MA0150.3.12
MA0150.3.13
MA0150.3.14
MA0150.3.15
MA0150.3.16
MA0150.3.17
MA0150.3.18
MA0150.3.19
MA0150.3.2
MA0150.3.20
MA0150.3.3
MA0150.3.4
MA0150.3.5
MA0150.3.6
MA0150.3.7
MA0150.3.8
MA0150.3.9
Publications: Portales-Casamar E, Kirov S, Lim J, Lithwick S, Swanson M.I, Ticoll A, Snoddy J, Wasserman W.W. PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation. Genome biology 8:R207 (2007). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.