Transcription Factor
| Accessions: | Q8C0Y1 (JASPAR 2024) |
| Names: | 5'-TG-3'-interacting factor 2, Homeobox protein TGIF2, TGF-beta-induced transcription factor 2, TGFB-induced factor 2, TGIF2_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 237 |
| Pfam Domains: | 19-75 Homeobox domain 36-75 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 MSDSDLGEDEGLLSLTGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNL 60 61 SVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSLLAVSVPA 120 121 PTNMLSLSVCSMPLHSGQGEKPAAPFPQVELESPKALVTPASTLTLLTRAEAGSPTGGLF 180 181 NTPPPTPPEQDKDDFSSFQLLVEVALQRAAEMELQKQQEPAPPLLHTPLPFVSENAK |
| Interface Residues: | 19, 20, 21, 22, 23, 24, 63, 64, 67, 70, 71, 72, 74, 75 |
| 3D-footprint Homologues: | 6fqp_B, 2ld5_A, 5zjt_E, 1mnm_C, 1puf_B, 1k61_B, 1le8_B, 1fjl_B, 6fqq_E, 2d5v_B, 4xrm_B, 7psx_B, 2hdd_A, 1du0_A, 2hos_A |
| Binding Motifs: | PH0170.1 aacyAGCTGTCAAwmc |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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