Transcription Factor

						

			
Accessions: Q03358 (JASPAR 2024)

			
Names: Homeobox protein Hox-8-1, Homeobox protein MSX-2, MSX2_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 267
Pfam Domains:   143-199 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MASPTKGGDLFSSDEEGPAVLAGPGPGPGGAEGSAEERRVKVSSLPFSVEALMSDKKPPK   60
  61 ESPAVPPDCASAGAVLRPLLLPGHGVRDAHSPGPLVKPFETASVKSENSEDGAPWIQEPG  120
 121 RYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLN  180
 181 LTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSGFSLPFPINSPLQAASIYGASY  240
 241 PFHRPVLPIPPVGLYATPVGYGMYHLS
Interface Residues: 128, 143, 144, 145, 146, 184, 185, 187, 188, 191, 192, 195, 196, 199
3D-footprint Homologues: 1e3o_C, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1fjl_B, 5zfz_A, 1zq3_P, 6m3d_C, 2lkx_A, 1nk2_P, 2ld5_A, 7q3o_C, 6es3_K, 4cyc_A, 1b72_A, 5flv_I, 5zjt_E, 4j19_B, 3a01_E, 7psx_B, 5hod_A, 3lnq_A, 1jgg_B, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1au7_A, 4xrs_G, 2hos_A, 2xsd_C, 1le8_A, 7xrc_C, 3l1p_A, 1o4x_A, 8g87_X, 1le8_B, 1du0_A, 4qtr_D, 1mnm_C, 1puf_B, 1k61_B
Binding Motifs: PH0107.1 vmagACyAATTAgykht
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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