Transcription Factor

Accessions: Q8VHG6 (JASPAR 2024)
Names: Q8VHG6_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8VHG6
Length: 335
Pfam Domains: 95-151 Homeobox domain
Sequence:
(in bold interface residues)
1 MAEGPSLHPKLQVASNIPIELSSQIPQDPARNLAFQMCQNPLVTPGSTMQSRLSVPERNL 60
61 LQQESQGPSRQSGRMPQSDKYVNKQTGPMASRKFRKERTVYSKEQQCLLQKHFDECQYPN 120
121 EKKIVELALSVGVTKREIKIWFKNNGAKYRRMKLQNIKQSLPETNESSKAVSESTHFPGS 180
181 IPVVASDNGESMCSGTFGEDSIPKLNCSQASSLHCFQACDRDMCCPQEYQEYQEYLLDGH 240
241 APVTAWNSGQSAAVESQTDLAVAEGPVGLAYAAQAPEDAHNSGPCEDELWQRILEDLDTS 300
301 DDWLTLRNPSTPVYTTEVLDQSRPYSHEEVCYTHL
Interface Residues: 49, 51, 53, 55, 62, 64, 90, 92, 94, 95, 96, 97, 98, 100, 102, 104, 106, 136, 137, 139, 140, 143, 144, 147, 148, 149, 150, 151, 152, 153, 156
3D-footprint Homologues: 6x1j_A, 1fjl_B, 3d1n_M, 5zfz_A, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1nk2_P, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 6es3_K, 7q3o_C, 2ld5_A, 1puf_B, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 5flv_I, 3l1p_A, 5zjt_E, 4j19_B, 3a01_E, 1jgg_B, 5hod_A, 2hdd_A, 7psx_B, 1au7_A, 5jlw_D, 3rkq_B, 2r5y_A, 2xsd_C, 7xrc_C, 1e3o_C, 1le8_A, 1o4x_A, 1du0_A, 4qtr_D
Binding Motifs: PH0123.1 wbrgrGGGATTAAcwmh
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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