Transcription Factor
Accessions: | T049287_1.02 (CISBP 1.02), Q9WVG7 (JASPAR 2024) |
Names: | Osr1, T049287_1.02;, OSR1_MOUSE |
Organisms: | Mus musculus |
Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | experiment type:PBM, family:C2H2 ZF |
Length: | 266 |
Pfam Domains: | 175-197 Zinc finger, C2H2 type 189-213 Zinc-finger double domain 203-225 Zinc finger, C2H2 type 217-240 Zinc-finger double domain 231-253 Zinc finger, C2H2 type |
Sequence: (in bold interface residues) | 1 MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYP 60 61 AMHLPRSSFSKVPGAVSSLMDARFQLPAFPWFPHVIHPKPEITAGGSGAALKTKPRFDFA 120 121 NLALAATQEDPTKLGRGEGPGSPAGGLGALLDVTKLSPEKKPTRGRLPSKTKKEFVCKFC 180 181 GRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGF 240 241 CQSRTLAVHKTLHSQVKELKTSKIKC |
Interface Residues: | 152, 154, 155, 158, 160, 161, 164, 165, 175, 185, 186, 187, 188, 189, 191, 192, 193, 198, 199, 200, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 224, 241, 242, 243, 244, 245, 246, 248 |
3D-footprint Homologues: | 6ml4_A, 6wmi_A, 2i13_A, 1ubd_C, 2kmk_A, 6jnm_A, 3uk3_C, 8cuc_F, 7y3l_A, 7n5w_A, 1tf3_A, 5und_A, 2drp_D, 1g2f_F, 5k5i_A, 1tf6_A, 2gli_A, 1llm_D, 6blw_A, 5kkq_D, 6u9q_A, 4x9j_A, 1mey_C, 5kl3_A, 5ei9_F, 2jpa_A, 7eyi_G, 5v3j_F, 4m9v_C, 8h9h_G, 2lt7_A, 7y3m_I, 6e94_A, 7ysf_A, 6a57_A, 7w1m_H, 1yuj_A, 8gn3_A, 5yel_A, 7txc_E, 2wbs_A, 1f2i_J, 5yj3_D, 8ssq_A |
Binding Motifs: | PB0050.1 htwwACrGTAGCwmwr PB0154.1 ryayGCTACywrmwhm M0431_1.02 acrGwAGca |
Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
Related annotations: | PaperBLAST |
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