Transcription Factor
| Accessions: | TF2L1_MOUSE (HOCOMOCO 10), Q3UNW5 (JASPAR 2024) |
| Names: | CP2-related transcriptional repressor 1, CRTR-1, TF2L1_MOUSE, Transcription factor CP2-like protein 1 |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q3UNW5 |
| Length: | 479 |
| Pfam Domains: | 42-242 CP2 transcription factor |
| Sequence: (in bold interface residues) | 1 MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENGARLPPLQYVLCAATSPAVK 60 61 LHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEYQQLEGW 120 121 RWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPSKRASAFIQVHCISTEFTPRK 180 181 HGGEKGVPFRVQIDTFKQNESGDYSEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQ 240 241 EKEKYQPSYETTILTECSPWPDVPYQANNTPSPSYNGSPNSFGLREGNSSPNHPVEPLPL 300 301 GSDHLLPSASIQDAQQWLHRNRFSQFCWLFASFSGADLLKMSRDDLVQVCGPADGIRLFN 360 361 AIKGRNVRPKMTIYVCQELEQNQLPLPQKQDDSGDNSLCVYHAIFLEELTTLELTEKIAS 420 421 LYSIPPQHIHRVYRQGPAGIHVVVSNEMVQNFQDESCFILSTLKAESNDGYHIILKCGL |
| Interface Residues: | 220, 225, 228, 237, 241, 265, 291, 294, 322, 427, 428, 430, 431 |
| 3D-footprint Homologues: | 5mpf_B, 3j9x_A, 1ic8_B, 1zgw_A |
| Binding Motifs: | TF2L1_MOUSE.H10MO.C|M01384 rrrCyrGyywGArCyrGyyy MA0145.1 CCrGyyyrarCCrG MA0145.2 CCrGyyyrarCCrG |
| Binding Sites: | MA0145.1.1 MA0145.1.10 MA0145.1.11 MA0145.1.12 MA0145.1.13 MA0145.1.14 MA0145.1.15 MA0145.1.16 MA0145.1.17 MA0145.1.18 MA0145.1.19 MA0145.1.2 MA0145.1.20 MA0145.1.3 MA0145.1.4 MA0145.1.5 MA0145.1.6 MA0145.1.7 MA0145.1.8 MA0145.1.9 |
| Publications: | Chen X, Xu H, Yuan P, Fang F, Huss M, Vega V.B, Wong E, Orlov Y.L, Zhang W, Jiang J, Loh Y.H, Yeo H.C, Yeo Z.X, Narang V, Govindarajan K.R, Leong B, Shahab A, Ruan Y, Bourque G, Sung W.K, Clarke N.D, Wei C.L, Ng H.H. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-17 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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