Transcription Factor
| Accessions: | T061545_1.02 (CISBP 1.02), P32805 (JASPAR 2024) |
| Names: | FZF1, T061545_1.02;, FZF1_YEAST, Sulfite resistance protein 1, Zinc finger protein FZF1 |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:C2H2 ZF |
| Length: | 299 |
| Pfam Domains: | 12-36 C2H2-type zinc finger 12-36 Zinc finger, C2H2 type 29-53 Zinc-finger double domain 58-83 Zinc-finger double domain 73-94 C2H2-type zinc finger 74-94 Zinc finger, C2H2 type 74-94 Zinc-finger of C2H2 type 156-180 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MTDIGRTKSRNYKCSFDGCEKVYNRPSLLQQHQNSHTNQKPYHCDEPGCGKKFIRPCHLR 60 61 VHKWTHSQIKPKACTLCQKRFVTNQQLRRHLNSHERKSKLASRIDRKHEGVNANVKAELN 120 121 GKEGGFDPKLPSGSPMCGEEFSQGHLPGYDDMQVLQCPYKSCQKVTSFNDDLINHMLQHH 180 181 IASKLVVPSGDPSLKESLPTSEKSSSTDTTSIPQLSFSTTGTSSSESVDSTTAQTPTDPE 240 241 SYWSDNRCKHSDCQELSPFASVFDLIDHYDHTHAFIPETLVKYSYIHLYKPSVWDLFEY |
| Interface Residues: | 16, 24, 25, 26, 27, 28, 30, 31, 33, 34, 37, 53, 54, 55, 56, 57, 58, 60, 61, 62, 64, 65, 82, 83, 84, 85, 86, 87, 88, 89, 90, 109, 110, 111, 113, 114, 115, 116, 117, 118, 121, 142, 143, 144, 145, 148, 149, 152, 168, 169, 170, 171, 174, 177 |
| 3D-footprint Homologues: | 2kmk_A, 7w1m_H, 8cuc_F, 7n5w_A, 1tf3_A, 5ei9_F, 6jnm_A, 5und_A, 1ubd_C, 7eyi_G, 6a57_A, 1mey_C, 2gli_A, 8gn3_A, 1f2i_J, 6blw_A, 5kkq_D, 2lt7_A, 6u9q_A, 4x9j_A, 1g2f_F, 5kl3_A, 1tf6_A, 8h9h_G, 7y3m_I, 2i13_A, 6e94_A, 7ysf_A, 6wmi_A, 2jpa_A, 5yel_A, 3uk3_C, 7y3l_A, 8ssq_A, 1llm_D, 6ml4_A, 5v3j_F, 7txc_E, 2wbs_A, 4m9v_C, 5k5i_A, 5yj3_D |
| Binding Motifs: | MA0298.1 CTATCA M0521_1.02 rwTGATAGgk |
| Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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