Transcription Factor
| Accessions: | Q9VTW5 (JASPAR 2024) |
| Names: | LIM homeobox transcription factor 1 alpha, isoform B, Q9VTW5_DROME, RE70810p |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9VTW5 |
| Length: | 640 |
| Pfam Domains: | 275-329 LIM domain 334-388 LIM domain 425-481 Homeobox domain 448-477 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 MLEFYPMPTNLNPVGGSLYSLQQNHGGARFLDNPNPGSMTASSGNSLHLSNSNNNLPTSI 60 61 SGNNSPTATASLTGQHQQHQQQQHQQQQQHPHQQHQQHQQQHAASTTPVPINSCPTPTGH 120 121 SPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAASAAAVAAPSPAGTSVAT 180 181 SQLGGAVAAAIAAAAAAAAAATTPTSTGPAATGSGNANGSGNGNGNGNGNGNGNGNGNGG 240 241 GAATASAAAASKLSADCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCL 300 301 ACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPC 360 361 FVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQHCGFVGLDEEDLLRPRDG 420 421 RRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMK 480 481 KIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQELGGDSSGYLGGLDSTF 540 541 ASQPLNPNLPFSPDDYPANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSSG 600 601 NQHSHSHSNPHDMLANLNNSLINPIDKLYLMQNSYFSSEH |
| Interface Residues: | 425, 426, 427, 428, 429, 466, 467, 469, 470, 473, 474, 477, 478, 481 |
| 3D-footprint Homologues: | 1puf_A, 2h1k_B, 1fjl_B, 6a8r_A, 3cmy_A, 1ig7_A, 5zfz_A, 3lnq_A, 2lkx_A, 1zq3_P, 3d1n_M, 1jgg_B, 6m3d_C, 2ld5_A, 1nk2_P, 7q3o_C, 6es3_K, 5flv_I, 3l1p_A, 3a01_E, 7psx_B, 1au7_A, 5hod_A, 2hdd_A, 1b72_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 4cyc_A, 2d5v_B, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 8g87_X, 5zjt_E, 4qtr_D, 1puf_B, 4xrm_B, 1o4x_A, 1du0_A |
| Binding Motifs: | MA0178.1 TTAATTA |
| Binding Sites: | MA0178.1.1 MA0178.1.16 / MA0178.1.18 / MA0178.1.20 MA0178.1.8 MA0178.1.10 MA0178.1.11 / MA0178.1.12 MA0178.1.13 MA0178.1.14 MA0178.1.15 MA0178.1.17 MA0178.1.19 MA0178.1.2 MA0178.1.3 MA0178.1.4 MA0178.1.5 MA0178.1.6 MA0178.1.7 MA0178.1.9 |
| Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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