Transcription Factor

Accessions: Q02591 (JASPAR 2024)
Names: GSC_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 256
Pfam Domains: 161-217 Homeobox domain
Sequence:
(in bold interface residues)
1 MPASMFSIDNILAARPRCKDAVLPVAPSAAAPVVFPALHGDSLYGAGGGTSSDYGAFYPR 60
61 PVAPGGAGLPAAVGSSRLGYNSYFYGQLHVQAAPVGPACCGAVPPLGAQQCSCVPTPPGY 120
121 EGPGSVLVSPVPHQMLPYMNVGTLSRTELQLLNQLHCRRKRRHRTIFTDEQLEALENLFQ 180
181 ETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKRSSSEESENAEKWNKTSSKAS 240
241 PEKREEEGKSDLDSDS
Interface Residues: 80, 82, 83, 85, 160, 161, 162, 163, 164, 202, 203, 205, 206, 209, 210, 213, 214, 217
3D-footprint Homologues: 2h7g_X, 4j19_B, 1ig7_A, 6a8r_A, 3cmy_A, 3d1n_M, 1puf_A, 5zfz_A, 2h1k_B, 1puf_B, 1fjl_B, 2lkx_A, 1zq3_P, 1jgg_B, 1nk2_P, 3lnq_A, 6es3_K, 7q3o_C, 2ld5_A, 2hdd_A, 7psx_B, 5jlw_D, 3rkq_B, 2r5y_A, 2d5v_B, 4xrs_G, 2hos_A, 4cyc_A, 6m3d_C, 1au7_A, 5flv_I, 3l1p_A, 5zjt_E, 3a01_E, 1b72_A, 5hod_A, 1e3o_C, 2xsd_C, 1le8_A, 7xrc_C, 8g87_X, 4qtr_D, 1o4x_A, 1du0_A, 6wig_A
Binding Motifs: PH0035.1 aawmryTAATCCsytwv
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.