Transcription Factor

Accessions: 1bdt_A (3D-footprint 20231221), 1par_A (3D-footprint 20231221)
Names: GENE-REGULATING PROTEIN ARC, RARC_BPP22, ARC REPRESSOR
Organisms: Enterobacteria phage P22
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P03050
Length: 52
Pfam Domains: 4-52 Arc-like DNA binding domain
Sequence:
(in bold interface residues)
1 MKGMSKMPQFNLRWPREVLDLVRKVAEENGRSVNSEIYQRVMESFKKEGRIG
Interface Residues: 4, 5, 9, 11, 13, 34, 35, 38
3D-footprint Homologues: 1bdt_C, 3qoq_B, 1o4x_B
Binding Motifs: 1bdt_ABCD TTaTAGAannnnTCTACcA
1par_ABCD TGTTAGAannnnTCTAyyA
Publications: Schildbach J.F, Karzai A.W, Raumann B.E, Sauer R.T. Origins of DNA-binding specificity: role of protein contacts with the DNA backbone. Proceedings of the National Academy of Sciences of the United States of America 96:811-7 (1999). [Pubmed]

Raumann B.E, Rould M.A, Pabo C.O, Sauer R.T. DNA recognition by beta-sheets in the Arc repressor-operator crystal structure. Nature 367:754-7 (1994). [Pubmed]
Related annotations: PaperBLAST

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