Transcription Factor

Accessions: ZNF71 (humanC2H2ZF-ChIP Feb2015)
Names: ENSG00000197951, Q9NQZ8, ZNF71
Organisms: Homo sapiens
Libraries: humanC2H2ZF-ChIP Feb2015 1
1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed]
Notes: TF family: C2H2 experiment: ChIP-seq/MEME/B1H-RC
Length: 489
Pfam Domains: 130-152 C2H2-type zinc finger
130-150 C2H2-type zinc finger
130-152 Zinc finger, C2H2 type
145-167 Zinc-finger double domain
157-172 C2H2-type zinc finger
158-180 Zinc finger, C2H2 type
172-196 Zinc-finger double domain
186-208 Zinc finger, C2H2 type
186-208 C2H2-type zinc finger
186-208 C2H2-type zinc finger
200-224 Zinc-finger double domain
214-236 Zinc finger, C2H2 type
214-236 C2H2-type zinc finger
214-232 C2H2-type zinc finger
228-252 Zinc-finger double domain
242-252 C2H2-type zinc finger
242-264 Zinc finger, C2H2 type
242-264 C2H2-type zinc finger
257-280 Zinc-finger double domain
270-280 C2H2-type zinc finger
270-292 Zinc finger, C2H2 type
270-292 C2H2-type zinc finger
284-308 Zinc-finger double domain
298-320 C2H2-type zinc finger
298-320 Zinc finger, C2H2 type
298-320 C2H2-type zinc finger
312-336 Zinc-finger double domain
326-348 C2H2-type zinc finger
326-348 Zinc finger, C2H2 type
326-348 C2H2-type zinc finger
342-364 Zinc-finger double domain
353-374 C2H2-type zinc finger
354-376 Zinc finger, C2H2 type
354-376 C2H2-type zinc finger
368-392 Zinc-finger double domain
381-404 C2H2-type zinc finger
382-404 Zinc finger, C2H2 type
382-404 C2H2-type zinc finger
397-420 Zinc-finger double domain
410-432 Zinc finger, C2H2 type
410-432 C2H2-type zinc finger
410-430 C2H2-type zinc finger
426-447 Zinc-finger double domain
438-460 Zinc finger, C2H2 type
438-460 C2H2-type zinc finger
438-453 C2H2-type zinc finger
452-477 Zinc-finger double domain
466-486 C2H2-type zinc finger
466-488 Zinc finger, C2H2 type
466-488 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MKELDPKNDISEDKLSVVGEATGGPTRNGARGPGSEGVWEPGSWPERPRGDAGAEWEPLG 60
61 IPQGNKLLGGSVPACHELKAFANQGCVLVPPRLDDPTEKGACPPVRRGKNFSSTSDLSKP 120
121 PMPCEEKKTYDCSECGKAFSRSSSLIKHQRIHTGEKPFECDTCGKHFIERSSLTIHQRVH 180
181 TGEKPYACGDCGKAFSQRMNLTVHQRTHTGEKPYVCDVCGKAFRKTSSLTQHERIHTGEK 240
241 PYACGDCGKAFSQNMHLIVHQRTHTGEKPYVCPECGRAFSQNMHLTEHQRTHTGEKPYAC 300
301 KECGKAFNKSSSLTLHQRNHTGEKPYVCGECGKAFSQSSYLIQHQRFHIGVKPFECSECG 360
361 KAFSKNSSLTQHQRIHTGEKPYECYICKKHFTGRSSLIVHQIVHTGEKPYVCGECGKAFS 420
421 QSAYLIEHQRIHTGEKPYRCGQCGKSFIKNSSLTVHQRIHTGEKPYRCGECGKTFSRNTN 480
481 LTRHLRIHT
Interface Residues: 130, 141, 142, 143, 144, 147, 151, 168, 169, 171, 172, 175, 196, 197, 198, 199, 200, 202, 203, 224, 225, 226, 227, 228, 230, 231, 232, 233, 234, 237, 253, 254, 255, 256, 258, 259, 280, 281, 282, 283, 284, 287, 308, 309, 310, 311, 312, 315, 336, 337, 338, 339, 340, 343, 346, 364, 365, 366, 367, 368, 371, 393, 395, 396, 398, 399, 405, 419, 420, 421, 422, 423, 424, 427, 431, 448, 449, 450, 451, 452, 453, 455, 476, 477, 478, 479, 480, 482, 483
3D-footprint Homologues: 2kmk_A, 8ssu_A, 2i13_A, 8gn3_A, 8cuc_F, 7y3l_A, 3uk3_C, 2gli_A, 1g2f_F, 5k5l_F, 7w1m_H, 6ml4_A, 1llm_D, 6wmi_A, 7n5w_A, 6blw_A, 5k5i_A, 4m9v_C, 2jpa_A, 8ssq_A, 5ei9_F, 7txc_E, 5kl3_A, 1tf3_A, 5und_A, 1tf6_A, 5v3j_F, 4x9j_A, 2wbs_A, 1mey_C, 1f2i_J, 5kkq_D, 6u9q_A, 7y3m_I, 6e94_A, 7ysf_A, 5yel_A, 5yj3_D, 7eyi_G, 8h9h_G, 2lt7_A, 1ubd_C, 6jnm_A, 6a57_A, 2drp_D
Binding Motifs: ZNF71_ChIP rGRAAayGAAA
Related annotations: PaperBLAST

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