Transcription Factor

Accessions: T061534_1.02 (CISBP 1.02), Q03125 (JASPAR 2024)
Names: NRG1, T061534_1.02;, NRG1_YEAST, Transcriptional regulator NRG1, Zinc finger protein MSS1
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 231
Pfam Domains: 174-196 Zinc finger, C2H2 type
174-192 C2H2-type zinc finger
188-214 Zinc-finger double domain
202-226 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MFYPYNYSNLNVSTMPALPGISAFDGMQDEENVEISPERKYQTLLPVLTNSHVVENELKH 60
61 KLNKTAFDFRYQTKSENGSEKWEPKYLITPNLQTRSVSFDNSSVQYNSDSSEKSSLSQLT 120
121 CNSSIIQQPENGIVSNDAYNKMANSRYSLKTRKQRTDPRNTLSDEEDLEQRRKYICKICA 180
181 RGFTTSGHLARHNRIHTGEKNHCCPYKGCTQRFSRHDNCLQHYRTHLKKGQ
Interface Residues: 162, 164, 165, 168, 184, 185, 186, 187, 188, 190, 191, 192, 195, 214, 215, 216, 217, 218, 220, 221, 222, 223, 225
3D-footprint Homologues: 2jpa_A, 5kl3_A, 7n5w_A, 5v3j_F, 3uk3_C, 2kmk_A, 7ysf_A, 1g2f_F, 7w1m_H, 6jnm_A, 8cuc_F, 7y3l_A, 6ml4_A, 1ubd_C, 8gn3_A, 6blw_A, 5ei9_F, 1mey_C, 6u9q_A, 2drp_D, 1f2i_J, 7txc_E, 6e94_A, 5kkq_D, 6wmi_A, 5yj3_D, 2gli_A, 8ssq_A, 4x9j_A, 2i13_A, 8ssu_A, 1llm_D, 5und_A, 8h9h_G, 4m9v_C, 7eyi_G, 7y3m_I, 1tf3_A, 2lt7_A, 1tf6_A, 6a57_A, 2wbs_A
Binding Motifs: MA0347.1 ytvrrymAGGGTCCwtbgcw
M0505_1.02 wmaGGGwcy
MA0347.2 dwmAGGGTCCdwt
MA0347.3 mAGGGTCC
Binding Sites: MA0347.3.20 / MA0347.3.7
MA0347.3.6
MA0347.3.5
MA0347.3.19
MA0347.3.14 / MA0347.3.16 / MA0347.3.18 / MA0347.3.8
MA0347.3.13 / MA0347.3.15
MA0347.2.1 / MA0347.2.2
MA0347.2.10 / MA0347.2.14
MA0347.2.11 / MA0347.2.15
MA0347.2.12 / MA0347.2.16
MA0347.2.13 / MA0347.2.15 / MA0347.2.17 / MA0347.2.19
MA0347.2.14 / MA0347.2.18
MA0347.2.16 / MA0347.2.20
MA0347.2.17
MA0347.2.18
MA0347.2.19
MA0347.2.2 / MA0347.2.4
MA0347.2.20
MA0347.2.3 / MA0347.2.5
MA0347.2.4 / MA0347.2.6
MA0347.2.5 / MA0347.2.7
MA0347.2.6 / MA0347.2.8
MA0347.2.7 / MA0347.2.9
MA0347.2.10 / MA0347.2.8
MA0347.2.12 / MA0347.2.9
MA0347.2.1
MA0347.2.11
MA0347.2.13
MA0347.2.3
MA0347.3.1
MA0347.3.10 / MA0347.3.11 / MA0347.3.2 / MA0347.3.3
MA0347.3.12
MA0347.3.17 / MA0347.3.4
MA0347.3.9
Publications: Newburger D.E, Bulyk M.L. UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Nucleic acids research 37:D77-82 (2009). [Pubmed]
Related annotations: PaperBLAST

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