Transcription Factor

Accessions: T100214_1.02 (CISBP 1.02), P34161 (JASPAR 2024)
Names: T100214_1.02;, YOX1, YOX1_YEAST
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:Homeodomain
Length: 385
Pfam Domains: 177-233 Homeobox domain
Sequence:
(in bold interface residues)
1 MSQETKMLPSLSSLLSGTEISSSPVSPSFTNPRTSFHLDDRGTIKLPPLNTSINRPRSVE 60
61 SALRHTVTSLHENSSAYGDDMLKHTQSDSALSSQLNSSQETVDESHENLLLTPLNSKKRD 120
121 YSVSSKKNDILTPLSAAKSIIIPSASKEKRRAFAFITHSQETFPKKEPKIDNAPLARRKR 180
181 RRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQRIATSK 240
241 STTIIQTVSPPSPPLDVHATPLASRVKADILRDGSSCSRSSSSSPLENTPPRPHHSLNRR 300
301 SSTPSIKRSQALTFHLNPQKKTLTPVKTSPNSRVNKLINSIDHSPSKAKRPVSNPSGSPK 360
361 RKRKFGFKIVDQQPLKDLDPNAFRG
Interface Residues: 177, 178, 179, 180, 181, 182, 218, 219, 221, 222, 225, 226, 229, 230, 231, 232, 233, 235
3D-footprint Homologues: 5zfz_A, 4j19_B, 2h1k_B, 3cmy_A, 1puf_A, 6a8r_A, 4cyc_A, 1fjl_B, 3lnq_A, 2lkx_A, 1jgg_B, 3d1n_M, 2ld5_A, 1nk2_P, 1b72_A, 5hod_A, 1puf_B, 3rkq_B, 3l1p_A, 5jlw_D, 7xrc_C, 1ig7_A, 1e3o_C, 1le8_A, 7q3o_C, 1au7_A, 2xsd_C, 3a01_E, 6m3d_C, 5flv_I, 1o4x_A, 8g87_X, 1du0_A, 5zjt_E, 4qtr_D, 2hdd_A, 7psx_B, 2r5y_A, 4xrm_B, 6es3_K, 4xrs_G, 2hos_A
Binding Motifs: M1138_1.02 aTtAATTa
MA0433.1 yTAATTaa
MA0433.2 yTAATTa
Publications: Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed]
Related annotations: PaperBLAST

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