Transcription Factor

Accessions: Q9FR97 (JASPAR 2024), T12843 (AthalianaCistrome v4_May2016)
Names: AtMYB65, Myb-related protein 65, MYB65_ARATH, Transcription factor MYB65, AT3G11440, MYB65, T12843;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:MYB
Length: 553
Pfam Domains: 43-90 Myb-like DNA-binding domain
46-106 Myb-like DNA-binding domain
96-139 Myb-like DNA-binding domain
100-143 Myb-like DNA-binding domain
Sequence:
(in bold interface residues)
1 MSYTTATADSDDGMHSSIHNESPAPDSISNGCRSRGKRSVLKKGPWTSTEDGILIDYVKK 60
61 HGEGNWNAVQKHTSLARCGKSCRLRWANHLRPNLKKGAFSQEEEQLIVEMHAKMGNKWAQ 120
121 MAEHLPGRTDNEIKNYWNTRIKRRQRAGLPLYPPEIYVDDLHWSEEYTKSNIIRVDRRRR 180
181 HQDFLQLGNSKDNVLFDDLNFAASLLPAASDLSDLVACNMLGTGASSSRYESYMPPILPS 240
241 PKQIWESGSRFPMCSSNIKHEFQSPEHFQNTAVQKNPRSCSISPCDVDHHPYENQHSSHM 300
301 MMVPDSHTVTYGMHPTSKPLFGAVKLELPSFQYSETSAFDQWKTTPSPPHSDLLDSVDAY 360
361 IQSPPPSQVEESDCFSSCDTGLLDMLLHEAKIKTSAKHSLLMSSPQKSFSSTTCTTNVTQ 420
421 NVPRGSENLIKSGEYEDSQKYLGRSEITSPSQLSAGGFSSAFAGNVVKTEELDQVWEPKR 480
481 VDITRPDVLLASSWLDQGCYGIVSDTSSMSDALALLGGDDIGNSYVTVGSSSGQAPRGVG 540
541 SYGWTNMPPVWSL
Interface Residues: 43, 78, 79, 80, 81, 83, 84, 87, 88, 89, 130, 131, 134, 135, 138, 139, 140
3D-footprint Homologues: 1w0t_A, 3osg_A, 1vfc_A, 2kdz_A, 7xur_A, 3zqc_A, 6kks_A, 1mse_C
Binding Motifs: M0533 / MA1177.1 ayyrTAACcGhmw
M0508 aTAACcGwmwmhrwa
MA1177.2 TAACcGhm
Binding Sites: MA1177.2.20
MA1177.2.8
MA1177.1.1
MA1177.1.10 / MA1177.1.3
MA1177.1.11
MA1177.1.12 / MA1177.1.13
MA1177.1.14 / MA1177.1.16
MA1177.1.15
MA1177.1.17
MA1177.1.18
MA1177.1.19
MA1177.1.2
MA1177.1.20
MA1177.1.4 / MA1177.1.8
MA1177.1.5
MA1177.1.6
MA1177.1.7
MA1177.1.9
MA1177.2.1
MA1177.2.10
MA1177.2.11
MA1177.2.12
MA1177.2.13
MA1177.2.14
MA1177.2.15
MA1177.2.16
MA1177.2.17
MA1177.2.18
MA1177.2.19
MA1177.2.2
MA1177.2.3
MA1177.2.4
MA1177.2.5
MA1177.2.6
MA1177.2.7
MA1177.2.9
Publications: Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Related annotations: PaperBLAST

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