Transcription Factor

Accessions: CEBPG (HT-SELEX2 May2017)
Names: CEBPG, ENSG00000153879
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4
Length: 105
Pfam Domains: 22-74 Basic region leucine zipper
25-80 bZIP transcription factor
Sequence:
(in bold interface residues)
1 GGGKAVAPSKQSKKSSPMDRNSDEYRQRRERNNMAVKKSRLKSKQKAQDTLQRVNQLKEE 60
61 NERLEAKIKLLTKELSVLKDLFLEHAHNLADNVQSISTENTTADG
Interface Residues: 28, 29, 32, 33, 35, 36, 39, 40
3D-footprint Homologues: 2wt7_A, 6mg1_B, 1nwq_C, 2c9l_Z
Binding Motifs: CEBPG_2 brTTGCGyMAyg
CEBPG_4 crTTGCGymAyg
CEBPG_methyl_1 trTTGCGyAAyr
CEBPG_methyl_3 brTTGCGymAyg
Related annotations: PaperBLAST

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