Transcription Factor

						

			
Accessions: Q99853 (JASPAR 2024)

			
Names: Forkhead box protein B1, FOXB1_HUMAN, Transcription factor FKH-5
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q99853
Length: 325
Pfam Domains:    13-108 Fork head domain
Sequence: 
(in bold interface residues)		   1 MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNS   60
  61 LRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVLKSDHLAPS  120
 121 KPADAAQYLQQQAKLRLSALAASGTHLPQMPAAAYNLGGVAQPSGFKHPFAIENIIAREY  180
 181 KMPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPISMASGDYSA  240
 241 YGVPLKPLCHAAGQTLPAIPVPIKPTPAAVPALPALPAPIPTLLSNSPPSLSPTSSQTAT  300
 301 SQSSPATPSETLTSPASALHSVAVH
Interface Residues: 53, 56, 58, 59, 60, 62, 63, 64, 66, 67, 76, 83, 91, 92, 93, 95, 96, 101, 105, 108
3D-footprint Homologues: 3l2c_A, 7vox_H, 2hdc_A, 7vou_C, 2c6y_A, 7yze_A, 7cby_C, 3g73_A, 6ako_C, 7yzg_A, 7tdw_A, 7yz7_A, 6el8_A, 2uzk_A, 7tdx_A, 2a07_J, 7yzb_A, 6nce_A, 3co6_C, 3qrf_G, 5j2y_A
Binding Motifs: MA0845.1 wAwGTMAAyAt
			
Publications: Kaufmann E., Mueller D., Knoechel W. DNA recognition site analysis of Xenopus winged helix proteins. J. Mol. Biol. 248:239-254 (1995). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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