Transcription Factor
| Accessions: | esg (DrosophilaTF 1.1), T057672_1.02 (CISBP 1.02) |
| Names: | ESCA_DROME, Protein escargot, Protein fleabag, esg, T057672_1.02; |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, CISBP 1.02 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Uniprot: | P25932 |
| Notes: | experiment type:B1H, family:C2H2 ZF |
| Length: | 470 |
| Pfam Domains: | 309-331 Zinc finger, C2H2 type 309-331 C2H2-type zinc finger 309-333 C2H2-type zinc finger 344-366 Zinc finger, C2H2 type 344-366 C2H2-type zinc finger 344-366 C2H2-type zinc finger 358-381 Zinc-finger double domain 371-392 Zinc finger, C2H2 type 371-392 C2H2-type zinc finger 385-408 Zinc-finger double domain 398-420 Zinc finger, C2H2 type 398-420 C2H2-type zinc finger 398-420 C2H2-type zinc finger 412-437 Zinc-finger double domain 426-450 C2H2-type zinc finger 426-444 Zinc finger, C2H2 type 426-444 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MHTVEDMLVEKNYSKCPLKKRPVNYQFEAPQNHSNTPNEPQDLCVKKMEILEENPSEELI 60 61 NVSDCCEDEGVDVDHTDDEHIEEEDEDVDVDVDSDPNQTQAAALAAAAAVAAAAAASVVV 120 121 PTPTYPKYPWNNFHMSPYTAEFYRTINQQGHQILPLRGDLIAPSSPSDSLGSLSPPPHHY 180 181 LHGRASSVSPPMRSEIIHRPIGVRQHRFLPYPQMPGYPSLGGYTHTHHHHAPISPAYSEN 240 241 SYYSMRSMTPESSCSSSLPEDLSLKHKNLNLNLNTSQPGEQAAAKTGDMSPETMPNASAK 300 301 KDKNQPPRYQCPDCQKSYSTFSGLTKHQQFHCPAAEGNQVKKSFSCKDCDKTYVSLGALK 360 361 MHIRTHTLPCKCNLCGKAFSRPWLLQGHIRTHTGEKPFSCQHCHRAFADRSNLRAHLQTH 420 421 SDIKKYSCTSCSKTFSRMSLLTKHSEGGCPGGSAGSSSSSELNYAGYAEP |
| Interface Residues: | 319, 320, 322, 323, 326, 330, 344, 354, 355, 356, 357, 358, 360, 361, 363, 364, 367, 380, 381, 382, 383, 384, 387, 388, 408, 409, 410, 411, 412, 413, 414, 415, 416, 419, 436, 437, 438, 439, 440, 442, 443, 458, 459, 460, 461 |
| 3D-footprint Homologues: | 7w1m_H, 8ssq_A, 8ssu_A, 5kkq_D, 5yel_A, 2i13_A, 1ubd_C, 2kmk_A, 6jnm_A, 7n5w_A, 5und_A, 6ml4_A, 4x9j_A, 6blw_A, 5ei9_F, 7eyi_G, 8h9h_G, 7ysf_A, 6wmi_A, 2lt7_A, 6e94_A, 6a57_A, 2jpa_A, 3uk3_C, 1tf3_A, 8cuc_F, 7y3l_A, 5kl3_A, 1f2i_J, 5k5i_A, 2gli_A, 1g2f_F, 1tf6_A, 5v3j_F, 1llm_D, 2wbs_A, 6u9q_A, 1mey_C, 7txc_E, 4m9v_C, 7y3m_I, 2drp_D, 5yj3_D, 5k5l_F, 8gn3_A |
| Binding Motifs: | esg hrrCAGGTGyas M4948_1.02 aCAGGTG |
| Publications: | Fuse N, Hirose S, Hayashi S. Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot. Genes & development 8:2270-81 (1994). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.