Transcription Factor

Accessions: 4s04_B (3D-footprint 20231221), 4s04_E (3D-footprint 20231221), 4s04_F (3D-footprint 20231221), 4s05_A (3D-footprint 20231221), 4s05_B (3D-footprint 20231221)
Names: A0A0R4I965_KLEPN, DNA-binding transcriptional regulator BasR
Organisms: Klebsiella pneumoniae JM45
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: S5YJU7
Length: 219
Pfam Domains: 3-112 Response regulator receiver domain
147-216 Transcriptional regulatory protein, C terminal
Sequence:
(in bold interface residues)
1 MKILVIEDDALLLQGLILAMQSEGYVCDGVSTAHEAALSLASNHYSLIVLDLGLPDEDGL 60
61 HFLSRMRREKMTQPVLILTARDTLEDRISGLDTGADDYLVKPFALEELNARIRALLRRHN 120
121 NQGDNEISVGNLRLNVTRRLVWLGETALDLTPKEYALLSRLMMKAGSPVHREILYNDIYS 180
181 GDNEPATNTLEVHIHNLREKIGKSRIRTVRGFGYMLANN
Interface Residues: 187, 188, 189, 191, 192, 193, 195, 196, 210
3D-footprint Homologues: 8jo2_H, 4kfc_B, 7e1b_B, 4nhj_A, 8hih_Q, 5ed4_A, 8hml_B, 2z33_A, 6lxn_A
Binding Motifs: 4s04_B TAAGCAAG
4s04_EF TWAtnTTannnTAAGnAA
4s05_A TtAAt
4s05_AB CtTAGnnnannATTaA
Binding Sites: 4s04_G
4s05_C
4s05_D
4s04_H
4s04_C
4s04_D
Publications: Lou YC, Weng TH, Li YC, Kao YF, Lin WF, Peng HL, Chou SH, Hsiao CD, Chen C. Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA. Nat Commun : (2015). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.