Transcription Factor

						

			
Accessions: 3u3w_A (3D-footprint 20231221), 3u3w_B (3D-footprint 20231221)

			
Names: Helix-turn-helix domain-containing protein, Helix-turn-helix transcriptional regulator, Q45782_BACTU, Transcriptional activator PlcR protein, XRE family transcriptional regulator
Organisms: Bacillus thuringiensis
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: J3QW86
Length: 280
Pfam Domains:      5-58 Helix-turn-helix domain
     8-58 Helix-turn-helix
Sequence: 
(in bold interface residues)		   1 AEKLGSEIKKIRVLRGLTQKQLSENICHQSEVSRIESGAVYPSMDILQGIAAKLQIPIIH   60
  61 FYEVLIYSDIERKKQFKDQVIMLCKQKRYKEIYNKVWNELKKEEYHPEFQQFLQWQYYVA  120
 121 AYVLKKVDYEYCILELKKLLNQQLTGIDVYQNLYIENAIANIYAENGYLKKGIDLFEQIL  180
 181 KQLEALHDNEEFDVKVRYNHAKALYLDSRYEESLYQVNKAIEISCRINSMALIGQLYYQR  240
 241 GECLRKLEYEEAEIEDAYKKASFFFDILEMHAYKEALVNK
Interface Residues: 20, 28, 29, 30, 31, 33, 34, 40
3D-footprint Homologues: 6w1f_A, 3s8q_A, 3u3w_B, 6w1a_A
Binding Motifs: 3u3w_AB trTGAAnnnnTGCATa
3u3w_B TTCaya
Binding Sites: 3u3w_Y
3u3w_Z
			
Publications: Grenha R, Slamti L, Nicaise M, Refes Y, Lereclus D, Nessler S. Structural basis for the activation mechanism of the PlcR virulence regulator by the quorum-sensing signal peptide PapR. Proceedings of the National Academy of Sciences of the United States of America 110:1047-52 (2013). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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