Transcription Factor
| Accessions: | STAT6_MOUSE (HOCOMOCO 10), P52633 (JASPAR 2024) |
| Names: | STAT6_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P52633 |
| Length: | 837 |
| Pfam Domains: | 2-114 STAT protein, protein interaction domain 126-271 STAT protein, all-alpha domain 273-527 STAT protein, DNA binding domain 538-616 SH2 domain |
| Sequence: (in bold interface residues) | 1 MSLWGLISKMSPEKLQRLYVDFPQRLRHLLADWLESQPWEFLVGSDAFCYNMASALLSAT 60 61 VQRLQATAGEQGKGNSILPHISTLESIYQRDPLKLVATIRQILQGEKKAVIEEFRHLPGP 120 121 FHRKQEELKFTTALGRLQHRVRETRLLRESLQQGAKTGQVSLQNLIDPPVNGPGPSEDLA 180 181 TMLQGTVGDLEATQALVLKRIQIWKRQQQLAGNGTPFEESLAGLQERCESLVEIYSQLQQ 240 241 EIGAASGELEPKTRASLISRLDEVLRTLVTSSFLVEKQPPQVLKTQTKFQAGVRFLLGLQ 300 301 FLGTSAKPPMVRADMVTEKQARELSLAQGPGTGVESTGEIMNNTVPLENSIPSNCCSALF 360 361 KNLLLKKIKRCERKGTESVTEEKCAVLFSTSFTLGPNKLLIQLQALSLPLVVIVHGNQDN 420 421 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTSRGLLPEHFLFLAQK 480 481 IFNDNSLSVEAFQHRCVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG 540 541 FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSSQIENIQPFSAKDLSIR 600 601 SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVSTTIKMTVERDQPLPTPE 660 661 PQMPAMVPPYDLGMAPDASMQLSSDMGYPPQSIHSFQSLEESMSVLPSFQEPHLQMPPNM 720 721 SQITMPFDQPHPQGLLQCQSQEHAVSSPEPMLCSDVTMVEDSCLTQPVGGFPQGTWVSED 780 781 MYPPLMPPTEQDLTKLLLENQGEAGGSLGSQPLLQPSPYGQSGISLSHLDLRTNPSW |
| Interface Residues: | 284, 377, 414, 415, 416, 417, 418 |
| 3D-footprint Homologues: | 1bf5_A, 1bg1_A, 4y5w_B |
| Binding Motifs: | MA0520.1 swyTTCywsaGAAmy STAT6_MOUSE.H10MO.C|M01369 abTTCywsaGAA MA0520.2 TTCywsaGAA |
| Binding Sites: | MA0520.1.1 MA0520.1.10 MA0520.1.11 MA0520.1.12 MA0520.1.13 MA0520.1.14 MA0520.1.15 MA0520.1.16 MA0520.1.17 MA0520.1.18 MA0520.1.19 MA0520.1.2 MA0520.1.20 MA0520.1.3 MA0520.1.4 MA0520.1.5 MA0520.1.6 MA0520.1.7 MA0520.1.8 MA0520.1.9 MA0520.2.1 MA0520.2.10 MA0520.2.11 MA0520.2.12 MA0520.2.13 MA0520.2.14 MA0520.2.15 MA0520.2.16 MA0520.2.17 MA0520.2.18 MA0520.2.19 MA0520.2.2 MA0520.2.20 MA0520.2.3 MA0520.2.4 MA0520.2.5 MA0520.2.6 MA0520.2.7 MA0520.2.8 MA0520.2.9 |
| Publications: | Kanai A, Suzuki K, Tanimoto K, Mizushima-Sugano J, Suzuki Y, Sugano S. Characterization of STAT6 target genes in human B cells and lung epithelial cells. DNA research : an international journal for rapid publication of reports on genes and genomes 18:379-92 (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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