Transcription Factor
Accessions: | O43435 (JASPAR 2024) |
Names: | T-box protein 1, T-box transcription factor TBX1, TBX1_HUMAN, Testis-specific T-box protein |
Organisms: | Homo sapiens |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | O43435 |
Length: | 398 |
Pfam Domains: | 112-297 T-box |
Sequence: (in bold interface residues) | 1 MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60 61 PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGGHVLKDKEVKAETSRNTPEREVE 360 361 LLRDAGGCVNLGLPCPAECQPFNTQGLVAGRTAGDRLC |
Interface Residues: | 137, 274, 275, 291, 294, 295 |
3D-footprint Homologues: | 4a04_B, 1h6f_B, 5flv_I, 1xbr_B, 6f59_B, 2x6v_A |
Binding Motifs: | MA0805.1 AGGTGTGA |
Publications: | Wilson V, Conlon FL. The T-box family. Genome Biol : (2002;3(6):REVIEWS3008.). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.