Transcription Factor

						

			
Accessions: CEBPE_HUMAN (HOCOMOCO 10), Q15744 (JASPAR 2024)

			
Names: C/EBP epsilon, CCAAT/enhancer-binding protein epsilon, CEBPE_HUMAN
Organisms: Homo sapiens
Libraries: HOCOMOCO 10 1, JASPAR 2024 2
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q15744
Length: 281
Pfam Domains:   204-256 Basic region leucine zipper
  205-261 bZIP transcription factor
Sequence: 
(in bold interface residues)		   1 MSHGTYYECEPRGGQQPLEFSGGRAGPGELGDMCEHEASIDLSAYIESGEEQLLSDLFAV   60
  61 KPAPEARGLKGPGTPAFPHYLPPDPRPFAYPPHTFGPDRKALGPGIYSSPGSYDPRAVAV  120
 121 KEEPRGPEGSRAASRGSYNPLQYQVAHCGQTAMHLPPTLAAPGQPLRVLKAPLATAAPPC  180
 181 SPLLKAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVLEYM  240
 241 AENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS
Interface Residues: 210, 211, 213, 214, 215, 217, 218, 220, 221, 222
3D-footprint Homologues: 1gd2_G, 2wt7_A, 6mg1_B, 1nwq_C, 5t01_B, 2c9l_Z, 5vpe_D, 2dgc_A
Binding Motifs: MA0837.1 rTTrCGCAAy
CEBPE_HUMAN.H10MO.A|M01051 tTkcGmAATmty
MA0837.2 kATTGCGCAATm
MA0837.3 ATTGCGCAAT
			
Publications: Osada S, Yamamoto H, Nishihara T, Imagawa M. DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family. J Biol Chem 271:3891-6 (1996). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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