Transcription Factor
| Accessions: | G5EF11 (JASPAR 2024) |
| Names: | E2F_TDP domain-containing protein, E2F-like, EFL-1, G5EF11_CAEEL, Mammalian transcription factor |
| Organisms: | Caenorhabditis elegans |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | G5EF11 |
| Length: | 342 |
| Pfam Domains: | 65-131 E2F/DP family winged-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MEDSYNDMEDPGFRQLSDMELQKALEMTKQSSIKNNLMLGLDNELDFDFDFDEDEDLDQP 60 61 QMGTRADKSLGLLAKRFIRMIQYSPYGRCDLNTAAEALNVRQKRRIYDITNVLEGIGLIE 120 121 KRSKNMIQWKGGDFMLNVKEGKRQSATTEEEDRMEQLKAEIEQLNKEEELIEQRQRWLQQ 180 181 SLRNMTESVENNKLSYVLRSQLAEIQGSDLTIGIQTRVGTQVRLSDPEQVEIHGGPSWCY 240 241 LKDPSGPLRAAIVSNHELHDFVQRERAKRPGEEHVDADAPDEMMDDSRYRNRRTINDDEM 300 301 FGFEQKVPAMKHLEPPPASDDYVYSSTGDEYRGDSIVDLYGD |
| Interface Residues: | 65, 99, 102, 103, 104, 105, 107 |
| 3D-footprint Homologues: | 1cf7_A, 4yo2_A, 1cf7_B |
| Binding Motifs: | MA0541.1 hrhksGCGssAAawt MA0541.2 sGCGssAAaw |
| Binding Sites: | MA0541.1.1 / MA0541.1.2 MA0541.1.10 / MA0541.1.8 / MA0541.1.9 MA0541.1.11 MA0541.1.12 / MA0541.1.13 MA0541.1.14 MA0541.1.15 MA0541.1.16 MA0541.1.17 MA0541.1.18 MA0541.1.19 MA0541.1.20 MA0541.1.3 MA0541.1.4 / MA0541.1.5 / MA0541.1.6 MA0541.1.7 MA0541.2.1 / MA0541.2.2 MA0541.2.10 / MA0541.2.8 / MA0541.2.9 MA0541.2.11 MA0541.2.12 / MA0541.2.13 MA0541.2.14 MA0541.2.15 MA0541.2.16 MA0541.2.17 MA0541.2.18 MA0541.2.19 MA0541.2.20 MA0541.2.3 MA0541.2.4 / MA0541.2.5 / MA0541.2.6 MA0541.2.7 |
| Publications: | Ceol C.J, Horvitz H.R. dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development. Molecular cell 7:461-73 (2001). [Pubmed] |
| Related annotations: | PaperBLAST |
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