Transcription Factor
| Accessions: | CREM (HT-SELEX2 May2017) |
| Names: | CREM, ENSG00000095794 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4 |
| Length: | 118 |
| Pfam Domains: | 57-113 bZIP transcription factor 62-110 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 ADGTQQFFVPGSQVVVQAATGDMPTYQIRAPTAALPQGVVMAASPGSLHSPQQLAEEATR 60 61 KRELRLMKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPKTDY |
| Interface Residues: | 65, 68, 69, 70, 72, 73, 76, 77 |
| 3D-footprint Homologues: | 1gd2_G, 5vpe_D, 1dh3_C, 7x5e_F, 5t01_B |
| Binding Motifs: | CREM_2 srTgACGTcAys CREM_methyl_1 srTGAyGTCAyg |
| Related annotations: | PaperBLAST |
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