Transcription Factor
| Accessions: | Q5TA89 (JASPAR 2024) |
| Names: | bHLHb38, Class B basic helix-loop-helix protein 38, Hairy and enhancer of split 5, HES5_HUMAN, Transcription factor HES-5 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q5TA89 |
| Length: | 166 |
| Pfam Domains: | 18-71 Helix-loop-helix DNA-binding domain 86-122 Hairy Orange |
| Sequence: (in bold interface residues) | 1 MAPSTVAVELLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKAD 60 61 ILEMAVSYLKHSKAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHFQ 120 121 RPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPACGLWRPW |
| Interface Residues: | 20, 21, 22, 24, 25, 28, 29 |
| 3D-footprint Homologues: | 1an4_A, 8osl_O, 4h10_B, 4h10_A, 7f2f_B, 8osl_P, 5gnj_I, 7xhv_B, 5nj8_C, 7xi3_B, 5v0l_B |
| Binding Motifs: | MA0821.1 yGrCACGTGCCr MA0821.2 grCACGTGyc |
| Publications: | Jones S. An overview of the basic helix-loop-helix proteins. Genome Biol : (2004;5(6):226.). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.