Transcription Factor
| Accessions: | Q9EQM3 (JASPAR 2024) |
| Names: | Homeobox protein NK-2 homolog D, Homeobox protein Nkx-2.4, NKX24_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 354 |
| Pfam Domains: | 189-245 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSLSPKHTTPFSVSDILSPIEETYKKFGGVMDGAPPGLGAPLGAAAYRAPPSGPSSQAAA 60 61 VAAGMQPPHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHSAMGSYCNGGLGNMGE 120 121 LPAYTDGMRGGAAAAATGWYGANTDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLA 180 181 PLHAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHR 240 241 YKMKRQAKDKAAQQLQQEGGLGPPPPPPPPSPRRVAVPVLVKDGKPCQNGAGTPTPGQGG 300 301 QQPQAPTPAPELEELSPSPPALHGPGGGLAALDAATGDYGGGVLGANLLYGRTW |
| Interface Residues: | 149, 150, 152, 153, 161, 165, 186, 188, 189, 190, 191, 192, 193, 230, 231, 233, 234, 237, 238, 241, 242, 245 |
| 3D-footprint Homologues: | 3l1p_A, 6m3d_C, 1puf_A, 4j19_B, 6a8r_A, 2h1k_B, 1fjl_B, 3cmy_A, 5zfz_A, 1ig7_A, 6fqp_B, 1mnm_C, 1zq3_P, 1jgg_B, 3lnq_A, 1nk2_P, 2lkx_A, 2ld5_A, 6es3_K, 7q3o_C, 5hod_A, 3a01_E, 1au7_A, 5jlw_D, 3rkq_B, 4xrs_G, 2hdd_A, 7psx_B, 1b72_A, 4cyc_A, 2r5y_A, 5flv_I, 2hos_A, 5zjt_E, 7xrc_C, 1e3o_C, 1le8_A, 2xsd_C, 6fqq_E, 4qtr_D, 1k61_B, 1o4x_A, 8g87_X, 1du0_A |
| Binding Motifs: | PH0113.1 waarCCACTTrAmwty |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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