Transcription Factor

Accessions: UP00504A (UniPROBE 20160601)
Names: Bagpipe, Bap, bgp, CG7902, Dmel\CG7902, dNK-3, Homeobox protein bagpipe, Homeobox protein NK-3, NK3
Organisms: Drosophila melanogaster
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: Bagpipe: Bagpipe is expressed in a segmented pattern in visceral muscle and in a subset of cardiac muscles. It’s Loss of activity results in segmental gaps in midgut visceral muscle.
Length: 89
Pfam Domains: 16-72 Homeobox domain
Sequence:
(in bold interface residues)
1 SESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVK 60
61 IWFQNRRYKTKRKQIQQHEAALLGASKRV
Interface Residues: 16, 17, 18, 19, 57, 58, 60, 61, 64, 65, 68, 69, 71, 72
3D-footprint Homologues: 3d1n_M, 1fjl_B, 5zfz_A, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 1jgg_B, 6es3_K, 1nk2_P, 2ld5_A, 7q3o_C, 1au7_A, 4xrs_G, 2hos_A, 4cyc_A, 1b72_A, 5flv_I, 3l1p_A, 5zjt_E, 3a01_E, 7psx_B, 5hod_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 7xrc_C, 2xsd_C, 1le8_A, 4j19_B, 1e3o_C, 1k61_B, 1o4x_A, 8g87_X, 1le8_B, 1du0_A, 4qtr_D, 1mnm_C, 1puf_B
Binding Motifs: UP00504A_1 GrayyrrCCACTTAryyytgaw
Binding Sites: AAGTACTT
ACACTTAA
ACCACTTA
ACTTAAGT
AGCACTTA
AGTACTTA
ATAAGTGG
CACTTAAA
CACTTAAC
CACTTAAG
CCACTTAA
CCACTTAC
CCACTTAG
CCCACTTA
GCACTTAA
GCCACTTA
GGCACTTA
GGTACTTA
GTACTTAA
TAAGTGGA
Publications: Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.