Transcription Factor
| Accessions: | NKX32_HUMAN (HOCOMOCO 10), P78367 (JASPAR 2024) |
| Names: | Bagpipe homeobox protein homolog 1, Homeobox protein NK-3 homolog B, Homeobox protein Nkx-3.2, NKX32_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 333 |
| Pfam Domains: | 207-263 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MAVRGANTLTSFSIQAILNKKEERGGLAAPEGRPAPGGTAASVAAAPAVCCWRLFGERDA 60 61 GALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASGAGLAG 120 121 GSLSLGQPVCELAASKDLEEEAAGRSDSEMSASVSGDRSPRTEDDGVGPRGAHVSALCSG 180 181 AGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLA 240 241 ASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLR 300 301 PPSLLPLQPSYYYPYYCLPGWALSTCAAAAGTQ |
| Interface Residues: | 79, 205, 206, 207, 208, 209, 210, 248, 249, 251, 252, 255, 256, 259, 260, 263, 264, 265 |
| 3D-footprint Homologues: | 6p4f_C, 6fqp_B, 4j19_B, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1fjl_B, 5zfz_A, 1ig7_A, 3lnq_A, 2lkx_A, 1jgg_B, 6m3d_C, 1nk2_P, 1zq3_P, 7q3o_C, 6es3_K, 2ld5_A, 3a01_E, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 4cyc_A, 1b72_A, 5flv_I, 3l1p_A, 7psx_B, 5zjt_E, 1e3o_C, 7xrc_C, 1au7_A, 2xsd_C, 1le8_A, 1le8_B, 6fqq_E, 1du0_A, 5hod_A, 4qtr_D, 1mnm_C, 1puf_B, 1k61_B, 8g87_X, 1o4x_A |
| Binding Motifs: | MA0122.2 rsCACTTAa NKX32_HUMAN.H10MO.C|M01378 arytAAGTGGv |
| Publications: | Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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