Transcription Factor

Accessions: CEBPB (HT-SELEX2 May2017)
Names: CEBPB, ENSG00000172216
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3
Length: 92
Pfam Domains: 17-70 Basic region leucine zipper
18-76 bZIP transcription factor
Sequence:
(in bold interface residues)
1 PAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERL 60
61 QKKVEQLSRELSTLRNLFKQLPEPLLASSGHC
Interface Residues: 25, 28, 29, 31, 32, 35, 36
3D-footprint Homologues: 6mg1_B, 1nwq_C, 2c9l_Z, 2dgc_A
Binding Motifs: CEBPB_2 brTTGCGyAAyr
CEBPB_methyl_1 yrTTGCGyAAyr
Related annotations: PaperBLAST

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