Transcription Factor
| Accessions: | CDX2_MOUSE (HOCOMOCO 10), P43241 (JASPAR 2024) |
| Names: | Caudal-type homeobox protein 2, CDX2_MOUSE, Homeobox protein CDX-2 |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 311 |
| Pfam Domains: | 13-178 Caudal like protein activation region 187-242 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAATANLDSAQS 60 61 PGPSWPTAYGAPLREDWNGYAPGGAAAANAVAHGLNGGSPAAAMGYSSPAEYHAHHHPHH 120 121 HPHHPAASPSCASGLLQTLNLGPPGPAATAAAEQLSPSGQRRNLCEWMRKPAQQSLGSQV 180 181 KTRTKDKYRVVYTDHQRLELEKEFHFSRYITIRRKSELAATLGLSERQVKIWFQNRRAKE 240 241 RKIKKKQQQQQQQQQQQPPQPPPQPSQPQPGALRSVPEPLSPVTSLQGSVPGSVPGVLGP 300 301 AGGVLNSTVTQ |
| Interface Residues: | 181, 183, 186, 187, 188, 189, 227, 228, 230, 231, 234, 235, 238, 239, 242 |
| 3D-footprint Homologues: | 2lkx_A, 1puf_A, 1nk2_P, 1zq3_P, 3lnq_A, 1jgg_B, 2ld5_A, 7q3o_C, 6es3_K, 2hdd_A, 5zfz_A, 3rkq_B, 2r5y_A, 6m3d_C, 5flv_I, 2hos_A, 1fjl_B, 5zjt_E, 4cyc_A, 7psx_B, 1ig7_A, 6a8r_A, 3a01_E, 2h1k_B, 5jlw_D, 4xrs_G, 3cmy_A, 7xrc_C, 1e3o_C, 1au7_A, 2xsd_C, 1le8_A, 1mnm_C, 1puf_B, 1k61_B, 3d1n_M, 8g87_X, 1b72_A, 5hod_A, 3l1p_A, 1o4x_A, 4qtr_D, 1le8_B, 1du0_A |
| Binding Motifs: | CDX2_MOUSE.H10MO.C|M01029 wTTTAyrr PH0013.1 drvgGymATAAAayky |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.