Transcription Factor
Accessions: | T025942_1.02 (CISBP 1.02), CEBPA_MOUSE (HOCOMOCO 10), P53566 (JASPAR 2024) |
Names: | Cebpa, T025942_1.02;, C/EBP alpha, CCAAT/enhancer-binding protein alpha, CEBPA_MOUSE |
Organisms: | Mus musculus, Rattus norvegicus |
Libraries: | CISBP 1.02 1, HOCOMOCO 10 2, JASPAR 2024 3 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | experiment type:PBM, family:bZIP |
Length: | 359 |
Pfam Domains: | 283-335 Basic region leucine zipper 288-339 bZIP transcription factor |
Sequence: (in bold interface residues) | 1 MESADFYEVEPRPPMSSHLQSPPHAPSNAAFGFPRGAGPAPPPAPPAAPEPLGGICEHET 60 61 SIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAAGPAGGGGDFDYPGAPAGPGGAVMSA 120 121 GAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQ 180 181 PPPPPPPPHPHASPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHAAPALGAA 240 241 GLPGPGSALKGLAGAHPDLRTGGGGGGSGAGAGKAKKSVDKNSNEYRVRRERNNIAVRKS 300 301 RDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESSLVKAMGNCA |
Interface Residues: | 289, 290, 293, 294, 296, 297, 300, 301 |
3D-footprint Homologues: | 2wt7_A, 1nwq_C, 6mg1_B, 5t01_B, 2c9l_Z, 5vpe_D, 2dgc_A |
Binding Motifs: | M0304_1.02 rTtdcghaAy CEBPA_MOUSE.H10MO.B|M01031 trTTktGmAAta MA0102.1 TtkygCAAyvyb MA0102.2 TtkygCAAy |
Binding Sites: | MA0102.1.1 MA0102.1.10 MA0102.1.11 MA0102.1.12 MA0102.1.13 MA0102.1.14 MA0102.1.15 MA0102.1.16 MA0102.1.17 MA0102.1.18 MA0102.1.2 MA0102.1.3 MA0102.1.4 MA0102.1.5 MA0102.1.6 MA0102.1.7 MA0102.1.8 MA0102.1.9 |
Publications: | Grange T., Roux J., Rigaud G., Pictet R. Cell-type specific activity of two glucocorticoid responsive units of rat tyrosine aminotransferase gene is associated with multiple binding sites for C/EBP and a novel liver-specific nuclear factor. Nucleic Acids Res. 19:131-139 (1991). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.