Transcription Factor

Accessions: T016893_1.02 (CISBP 1.02)
Names: HLH4C, T016893_1.02;
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:B1H, family:bHLH
Length: 167
Pfam Domains: 110-160 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MVYDMSHMAAGPPQSISLSRYYLVDDDEMIGPNNPHLVNEDYAASTTLDIDKRFQARMAC 60
61 ETAAQPAPPPPPTPAPRRRTTPIAHLDPSELVGLSREERRRRRRATLKYRTAHATRERIR 120
121 VEAFNVSFAELRKLLPTLPPDKKLSKIEILKLAICYIAYLNHVLETP
Interface Residues: 113, 114, 116, 117, 118, 120, 121
3D-footprint Homologues: 5i50_B, 6g1l_A, 4h10_A, 6od3_F, 4h10_B, 8osl_O, 8osl_P, 2ypa_B, 2ql2_A, 2ypa_A, 2ql2_D
Binding Motifs: M5011_1.02 GGhkCAGGTG
Related annotations: PaperBLAST

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