Transcription Factor
| Accessions: | O70477 (JASPAR 2024) |
| Names: | Homeobox protein PKNOX1, PBX/knotted homeobox 1, PKNX1_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O70477 |
| Length: | 436 |
| Pfam Domains: | 277-316 Homeobox KN domain 278-316 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSDPDAEGVSPPPIESQTPMDADKQAIYR 60 61 HPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVK 120 121 AIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAI 180 181 TGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQ 240 241 LQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTN 300 301 LTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPS 360 361 ELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALA 420 421 PTHISGLVLENSDSLQ |
| Interface Residues: | 260, 262, 263, 265, 304, 305, 307, 308, 311, 312, 313, 315, 316 |
| 3D-footprint Homologues: | 1puf_A, 6fqp_B, 4j19_B, 1mnm_C, 1puf_B, 2ld5_A, 1le8_A, 1au7_A, 1le8_B, 6fqq_E, 2d5v_B, 1fjl_B, 4xrm_B, 7psx_B, 1k61_B, 4xrs_G, 2lkx_A |
| Binding Motifs: | PH0140.1 wrmsAsCTGTCAawmc |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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