Transcription Factor
| Accessions: | Q62431 (JASPAR 2024) |
| Names: | ARI3A_MOUSE, ARID domain-containing protein 3A, AT-rich interactive domain-containing protein 3A, B-cell regulator of IgH transcription, Bright, Dead ringer-like protein 1 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 601 |
| Pfam Domains: | 242-331 ARID/BRIGHT DNA binding domain |
| Sequence: (in bold interface residues) | 1 MKLQAVMETLIQRQQRARQELEARQAPPPPPPEPTGVRARTTMTDEDREPENARMHRTQM 60 61 AALAAMRAAAAGLGHPSSPGGSEDGPPISGDEDTAREGTLSSPALHGSVLEGAGHAEGDR 120 121 HLMDVGSDDDDTKSKWEEQELEELGEEEEEEEEEDDFEEEEEEEEGLGPPESASLGTAGL 180 181 FTRKAPPAQAFRGDGGPRMLSGPERLGPGPAHPSHMASQMPPPDHGDWTFEEQFKQLYEL 240 241 DADPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWR 300 301 EITKGLNLPTSITSAAFTLRTQYMKYLYPYECERRGLSSPNELQAAIDSNRREGRRQSFG 360 361 GSLFAYSPSGAHSMLPSPKLPVTPLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPV 420 421 SLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESTEPPEKKMALVADEQQRLMQ 480 481 RAVQQSFLAMTAQLPMNIRINSQASESRQDSAVSLTSANGSNSISMSVEMNGIVYTGVLF 540 541 AQPPPPTAPSAPGKGGVSSIGTNTTTGSRTGASGSTVSGGQVGLPGVSTPTMSSTSNNSL 600 601 P |
| Interface Residues: | 300, 313, 314, 317, 318, 352 |
| 3D-footprint Homologues: | 2oeh_A, 1kqq_A |
| Binding Motifs: | PB0001.1 sgktTTAATTAAwmtwy PB0105.1 hmmvrtATcrdrtyk MA0151.1 ATyAAA |
| Binding Sites: | MA0151.1.1 MA0151.1.10 MA0151.1.11 MA0151.1.12 MA0151.1.13 MA0151.1.14 MA0151.1.15 MA0151.1.16 MA0151.1.17 MA0151.1.18 MA0151.1.19 MA0151.1.2 MA0151.1.20 MA0151.1.3 MA0151.1.4 MA0151.1.5 MA0151.1.6 MA0151.1.7 MA0151.1.8 MA0151.1.9 |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Herrscher R.F, Kaplan M.H, Lelsz D.L, Das C, Scheuermann R, Tucker P.W. The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family. Genes & development 9:3067-82 (1995). [Pubmed] |
| Related annotations: | PaperBLAST |
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