Transcription Factor
| Accessions: | P97460 (JASPAR 2024) |
| Names: | Neuronal PAS domain-containing protein 2, Neuronal PAS2, NPAS2_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P97460 |
| Length: | 816 |
| Pfam Domains: | 10-57 Helix-loop-helix DNA-binding domain 85-154 PAS fold 262-348 PAS fold |
| Sequence: (in bold interface residues) | 1 MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHN 60 61 EVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTDGSIIYVSDSITPLLGHL 120 121 PADVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEFLKSDNDLEFYCHLLRGSLNPK 180 181 EFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCHVPLGKDVCFIATVRLATPQFLKE 240 241 MCVADEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYNYYHIDDLELLARCH 300 301 QHLMQFGKGKSCCYRFLTKGQQWIWLQTHYYITYHQWNSKPEFIVCTHSVVSYADVRVER 360 361 RQELALEDPPTEAMHPSAVKEKDSSLEPPQPFNALDMGASGLPSSPSPSASSRSSHKSSH 420 421 TAMSEPTSTPTKLMAENSTTALPRPATLPQELPVQGLSQAATMPTALHSSASCDLTKQLL 480 481 LQSLPQTGLQSPPAPVTQFSAQFSMFQTIKDQLEQRTRILQANIRWQQEELHKIQEQLCL 540 541 VQDSNVQMFLQQPAVSLSFSSTQRPAAQQQLQQRPAAPSQPQLVVNTPLQGQITSTQVTN 600 601 QHLLRESNVISAQGPKPMRSSQLLPASGRSLSSLPSQFSSTASVLPPGLSLTTIAPTPQD 660 661 DSQCQPSPDFGHDRQLRLLLSQPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQVMFPSPD 720 721 SHPTNSSASTPVLLMGQAVLHPSFPASRPSPLQPAQAQQQPPPYLQAPTSLHSEQPDSLL 780 781 LSTFSQQPGTLGYAATQSTPPQPPRPSRRVSRLSES |
| Interface Residues: | 9, 11, 13, 14, 15, 17, 18, 21, 22, 45 |
| 3D-footprint Homologues: | 4zpk_B, 1a0a_B, 1an4_A, 7xi3_B, 4zpk_A, 7ssa_L, 8osl_O, 6g1l_A, 7xhv_B, 5nj8_D, 4h10_A, 7d8t_A, 5eyo_A, 7xi3_A, 5v0l_A, 4h10_B, 7f2f_B, 8osl_P, 5gnj_I, 5nj8_C, 5v0l_B |
| Binding Motifs: | MA0626.1 dsCACGTGtm MA0626.2 sCACGTGt |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.