Transcription Factor

Accessions: P05554 (JASPAR 2024)
Names: C/EBP alpha, CCAAT/enhancer-binding protein alpha, CEBPA_RAT
Organisms: Rattus norvegicus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P05554
Length: 358
Pfam Domains: 282-334 Basic region leucine zipper
287-338 bZIP transcription factor
Sequence:
(in bold interface residues)
1 MESADFYEAEPRPPMSSHLQSPPHAPSNAAFGFPRGAGPAPPPAPPAAPEPLGGICEHET 60
61 SIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAAGPAGGGGDFDYPGAPAGPGGAVMSA 120
121 GAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQ 180
181 PPPPPPPPHPHASPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPAMGAA 240
241 GLPGPGGSLKGLAGPHPDLRTGGGGGGGAGAGKAKKSVDKNSNEYRVRRERNNIAVRKSR 300
301 DKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESSLVKAMGNCA
Interface Residues: 288, 289, 292, 293, 295, 296, 299, 300
3D-footprint Homologues: 2wt7_A, 6mg1_B, 1nwq_C, 5t01_B, 2c9l_Z, 5vpe_D, 2dgc_A
Binding Motifs: MA0019.1 rrrTGCAATmcc
Binding Sites: MA0019.1.1
MA0019.1.10
MA0019.1.11
MA0019.1.12 / MA0019.1.13
MA0019.1.14
MA0019.1.15
MA0019.1.16
MA0019.1.17
MA0019.1.18
MA0019.1.19
MA0019.1.2
MA0019.1.20
MA0019.1.3
MA0019.1.4
MA0019.1.5
MA0019.1.6
MA0019.1.7
MA0019.1.8
MA0019.1.9
Publications: Ubeda M., Wang X.-Z., Zinszner H., Wu I., Habener J. F., Ron D. Stress-induced binding of the transcription factor CHOP to a novel DNA control element. Mol. Cell. Biol. 16:1479-1489 (1996). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.