Transcription Factor

Accessions: E2Fb (Athamap 20091028)
Names: AtE2F1, E2F transcription factor-1, E2F1, E2Fb, Transcription factor E2FB
Organisms: Arabidopsis thaliana
Libraries: Athamap 20091028 1
1 Bulow L, Engelmann S, Schindler M, Hehl R. AthaMap, integrating transcriptional and post-transcriptional data. Nucleic acids research 37:D983-6 (2009). [Pubmed]
Uniprot: Q9FV71
Length: 469
Pfam Domains: 129-194 E2F/DP family winged-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MSEEVPQQFPSSKRQLHPSLSSMKPPLVAPGEYHRFDAAETRGGGAVADQVVSDAIVIKS 60
61 TLKRKTDLVNQIVEVNELNTGVLQTPVSGKGGKAKKTSRSAKSNKSGTLASGSNAGSPGN 120
121 NFAQAGTCRYDSSLGLLTKKFINLIKQAEDGILDLNKAADTLEVQKRRIYDITNVLEGIG 180
181 LIEKTLKNRIQWKGLDVSKPGETIESIANLQDEVQNLAAEEARLDDQIRESQERLTSLSE 240
241 DENNKRLLFVTENDIKNLPCFQNKTLIAVKAPHGTTLEVPDPDEAGGYQRRYRIILRSTM 300
301 GPIDVYLVSQFEESFEDIPQADEPSNVPDEPSNVPDVPSNLPSTSGLPENHDVSMPMKEE 360
361 STERNMETQEVDDTQRVYSDIESHDFVDGIMKIVPPDLDMGVDYWFRSEVGEVSITDMWP 420
421 DESGPDWNQMITFDQDHAGPSDNKILEQPQTPSSPTPEESTATRSPTGS
Interface Residues: 129, 163, 165, 166, 167, 168, 170
3D-footprint Homologues: 4yo2_A, 1cf7_A, 1cf7_B
Binding Motifs: E2Fb WTTCCCGC
Binding Sites: E2Fb_1
E2Fb_3
E2Fb_4
E2Fb_2
Publications: de Jager S. M., Menges M., Bauer U. M., Murra J. A. Arabidopsis E2F1 binds a sequence present in the promoter of S-phase-regulated gene AtCDC6 and is a member of a multigene family with differential activities.. Plant Mol. Biol. 47:555-568 (2001). [Pubmed]

Mariconti L, Pellegrini B, Cantoni R, Stevens R, Bergounioux C, Cella R, Albani D. 2002. The E2F family of transcription factors from Arabidopsis thaliana. Novel and conserved components of the retinoblastoma/E2F pathway in plants. J Biol Chem. 277:9911-9. [Pubmed]

Egelkrout EM, Mariconti L, Settlage SB, Cella R, Robertson D, Hanley-Bowdoin L. 2002. Two E2F elements regulate the proliferating cell nuclear antigen promoter differently during leaf development. Plant Cell. 14:3225-36. [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.