Transcription Factor
| Accessions: | Q78DU3 (JASPAR 2024) |
| Names: | Homeobox protein unc-4 homolog, Homeobox protein Uncx4.1, UNC4_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 530 |
| Pfam Domains: | 110-166 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSAAAAAAAASVPFSIDGL 60 61 LSGSCAAAAASVVNPTPLLPAACGVAGESQPFKLADSGDPDKESPGCKRRRTRTNFTGWQ 120 121 LEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHN 180 181 SHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQSRHLHSPGGLSLHSAPSSDSD 240 241 SGGGGLSPEPPEPPPPTAAAKGPGAHGSGIAGSAPVPPGEPPAPGTCDPAFYPSQRSGAG 300 301 SQPRLGRPADKDTVPCGPGAAATAGLPKASPFSVESLLSDSPPRRKATPANAAATAGLDF 360 361 TPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGPELVPKDAPPAPPAPPAPPA 420 421 QASFGTFPGPGGAADPAFARRSPEVVASPGPPAPASFRDLTAAAAESGAGDCADVGTVCP 480 481 AASPPPPLETSPGPGPRAPSPPGEPATCGAAEPGAATGPSPPEGEEVDMD |
| Interface Residues: | 109, 110, 111, 112, 113, 151, 152, 154, 155, 158, 159, 162, 163, 166 |
| 3D-footprint Homologues: | 4j19_B, 3a01_E, 3d1n_M, 5zfz_A, 1fjl_B, 2h1k_B, 1ig7_A, 1puf_A, 6a8r_A, 3cmy_A, 1jgg_B, 1nk2_P, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 2hos_A, 1au7_A, 4cyc_A, 5flv_I, 3l1p_A, 1b72_A, 5zjt_E, 7psx_B, 5hod_A, 1e3o_C, 7xrc_C, 2xsd_C, 1o4x_A, 8g87_X, 1du0_A, 4qtr_D |
| Binding Motifs: | PH0173.1 vataaTTAATTAAygsg |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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