Transcription Factor
| Accessions: | T028113_1.02 (CISBP 1.02), Q94126 (JASPAR 2024) |
| Names: | ces-2, T028113_1.02;, Cell death specification protein 2, CES2_CAEEL, Transcription factor ces-2 |
| Organisms: | Caenorhabditis elegans |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:bZIP |
| Length: | 211 |
| Pfam Domains: | 115-168 Basic region leucine zipper 122-173 bZIP transcription factor |
| Sequence: (in bold interface residues) | 1 MDFHRALSALFTNQAAVQPLLGSLGFPFNDGTSILTTALAAQSGGKKLDTPLGILPFDSL 60 61 PTTNLLTPTKKIKLEDELCASPVSSRSSTVSSSHFSSPQRSPSRKMSVPIPEEKKDSAYF 120 121 ERRRKNNDAAKRSRDARRQKEEQIASKAHALERENMQLRGKVSSLEQEAAQLRFLLFSKI 180 181 SPANSEVSCESNDSTETNDSNDSKSDSTIEV |
| Interface Residues: | 122, 123, 126, 127, 129, 130, 133, 134 |
| 3D-footprint Homologues: | 2wt7_A, 6mg1_B, 1nwq_C, 5vpe_C |
| Binding Motifs: | M0358_1.02 ATTAyrTAA MA0922.1 ATTAyrTAA |
| Publications: | Metzstein M. M., Hengartner M. O., Tsung N., Ellis R. E., Horvitz H. R. Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2. Nature 382:545-547 (1996). [Pubmed] |
| Related annotations: | PaperBLAST |
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