Transcription Factor

Accessions: 3ere_D (3D-footprint 20231221)
Names: Arginine repressor, ARGR_MYCTU
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P9WPY8
Length: 156
Pfam Domains: 2-71 Arginine repressor, DNA binding domain
87-154 Arginine repressor, C-terminal domain
Sequence:
(in bold interface residues)
1 AANRAGRQARIVAILSSAQVRSQNELAALLAAEGIEVTQATLSRDLEELGAVKLRGADGG 60
61 TGIYVVPEDGSPVRGVSGGTDRMARLLGELLVSTDDSGNLAVLRTPPGAAHYLASAIDRA 120
121 ALPQVVGTIAGDDTILVVAREPTTGAQLAGMFENLR
Interface Residues: 38, 39, 40, 43, 44
3D-footprint Homologues: 2p5l_D, 3lap_B
Binding Motifs: 3ere_D TATgCa
Binding Sites: 3ere_A
3ere_B
Publications: Cherney L.T, Cherney M.M, Garen C.R, Lu G.J, James M.N. Crystal structure of the arginine repressor protein in complex with the DNA operator from Mycobacterium tuberculosis. Journal of molecular biology 384:1330-40 (2008). [Pubmed]
Related annotations: PaperBLAST

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