Transcription Factor

Accessions: T120854_1.02 (CISBP 1.02), UP00328A (UniPROBE 20160601), P34219 (JASPAR 2024)
Names: T120854_1.02;, TOD6, Hypothetical 59.2 kDa protein in PTC3-SAS3 intergenic region, Pbf1, YBL0509, YBL0513, PAC-binding factor 1, TOD6_YEAST, Transcriptional regulatory protein TOD6, Twin of DOT6
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, UniPROBE 20160601 2, JASPAR 2024 3
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Description: Myb domain-containing protein YBL054W
Notes: experiment type:PBM, family:Myb/SANT
Length: 525
Pfam Domains: 77-120 Myb-like DNA-binding domain
78-121 Myb-like DNA-binding domain
Sequence:
(in bold interface residues)
1 MTLPKLSSVSVSSGHVSANSHGFSILSKHPHPNNLVHSHSLSHTNAKSHLPISSTSTKEN 60
61 STNKEEAESLKKNNPSSWDPSDDIKLRHLKEIKNLGWKEIAHHFPNRTPNACQFRWRRLK 120
121 SGNLKSNKTAVIDINKLFGVYATGDATPSAGTPSAEEAVKEEAVEDEDITAGSSAIEDSP 180
181 PDFKPLVKPKYMDRKLITQRSTSTFSDHEPQHTKPRKLFVKPRSFSHSITTNTPNVKTAQ 240
241 QTNLSLYNTTSAKTNKAVNSNDYENIGLVPKIIIRSRRNSFIPSTQIPHSTTKTRKNSHS 300
301 VISSRRSSFNMMHSRRSSFNSHAPTEPISRRASLVVSPYMSPRRLSTSQSVHYHPQHQYY 360
361 LNPIASPNCKTDHANDKITHTRTFLDMQKFANKHPWSREDDEVLLNNTKDKQNHLSPLEI 420
421 SIVLPNNRSELEIQQRMDYLKRKGRVSGFHTNEGCKDEEEEDDIDPLHKENGINTPSQQS 480
481 QNYGMLEAKHDNPKSSELSSMTSANDIRNEQDELPGINSIFKNIF
Interface Residues: 75, 110, 111, 113, 114, 117, 119, 160
3D-footprint Homologues: 3osg_A, 3zqc_A, 1ign_A
Binding Motifs: MA0350.1 akbcwyasCTCATCGcsyywk
UP00328A_1 akbcwyasCTCATCGcsyywk
M1370_1.02 cgcGATGms
M1371_1.02 sscGATGs
MA0350.2 asCTCATCGc
Binding Sites: AGCTCATC
CCCATCGC
CCGATGAC
CCGATGAG
CCTCATCG
CGATGACC
CGATGAGA
CGATGAGC
CGATGCCC
CGCGATGA
CTCATCAC
CTCATCGA
CTCATCGC
CTCATCTC
GATGAGCC
GCGATGAC
GCGATGCC
GGCGATGA
TCATCGCA
CATCGATG
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]

Newburger D.E, Bulyk M.L. UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Nucleic acids research 37:D77-82 (2009). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.