Transcription Factor
| Accessions: | ATF3 (HT-SELEX2 May2017) |
| Names: | ATF3, ENSG00000162772 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3 |
| Length: | 139 |
| Pfam Domains: | 57-114 bZIP transcription factor 58-111 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 SLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDE 60 61 RKKRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLN 120 121 LHRPTCIVRAQNGRTPEDE |
| Interface Residues: | 65, 66, 69, 70, 72, 73, 76, 77, 80 |
| 3D-footprint Homologues: | 7x5e_E, 7x5e_F, 1skn_P, 2wt7_A, 6mg1_B, 1nwq_C, 5t01_B, 5vpe_C, 5vpe_D |
| Binding Motifs: | ATF3_2 grTGACGTCAyc ATF3_4 grTGACGTCAyc ATF3_methyl_1 gRTGAyGTCATc ATF3_methyl_3 grTGAyGTCAYc |
| Related annotations: | PaperBLAST |
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