Transcription Factor

						

			
Accessions: P54845 (JASPAR 2024)

			
Names: Neural retina-specific leucine zipper protein, NRL_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P54845
Length: 237
Pfam Domains:    67-102 Maf N-terminal region
  130-223 bZIP Maf transcription factor
Sequence: 
(in bold interface residues)		   1 MALPPSPLAMEYVNDFDLMKFEVKREPSEGRPGPPTASLGSTPYSSVPPSPTFSEPGMVG   60
  61 ATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAMELLQGQGPVPVDGPHGYYPGSPEE  120
 121 TGAQHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKR  180
 181 LQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTSSGPGSGDPSHLFL
Interface Residues: 165, 169, 170, 172, 173, 176, 177
3D-footprint Homologues: 2wt7_B, 7x5e_F, 4eot_A, 2wt7_A, 7x5e_E, 5vpe_D
Binding Motifs: MA0842.1 wwwttGCTGAc
MA0842.2 aawwrTGCTGACg
MA0842.3 awwrTGCTGACg
			
Publications: Rehemtulla A, Warwar R, Kumar R, Ji X, Zack DJ, Swaroop A. The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression. Proc Natl Acad Sci U S A 93:191-5 (1996). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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