Transcription Factor
| Accessions: | BMAL1_MOUSE (HOCOMOCO 10), Q9WTL8 (JASPAR 2024) |
| Names: | Arnt3, Aryl hydrocarbon receptor nuclear translocator-like protein 1, BMAL1_MOUSE, Brain and muscle ARNT-like 1 |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9WTL8 |
| Length: | 632 |
| Pfam Domains: | 81-132 Helix-loop-helix DNA-binding domain 156-259 PAS fold 353-441 PAS fold 357-442 PAS fold |
| Sequence: (in bold interface residues) | 1 MADQRMDISSTISDFMSPGPTDLLSGSLGTSGVDCNRKRKGSATDYQLDDFAFEESMDTD 60 61 KDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLT 120 121 VLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVS 180 181 ESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDIT 240 241 PGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKDRKSFCTIHSTGYLKSWPPT 300 301 KMGLDEDNEPDNEGCNLSCLVAIGRLHSHMVPQPANGEIRVKSMEYVSRHAIDGKFVFVD 360 361 QRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFI 420 421 TLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTAPPHSMDSMLPSGEGGP 480 481 KRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASS 540 541 PGGKKILNGGTPDIPSTGLLPGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPS 600 601 NDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL |
| Interface Residues: | 81, 83, 84, 85, 87, 88, 91, 92, 96, 116, 118 |
| 3D-footprint Homologues: | 1a0a_B, 1an4_A, 7ssa_L, 5nj8_D, 4h10_B, 7xq5_A, 6g1l_A, 5eyo_A, 1am9_A, 4zpk_A, 8osl_O, 7d8t_A, 5gnj_I, 7xi3_A, 5v0l_A, 7f2f_B, 4h10_A, 8osl_P, 5nj8_C, 4zpr_B, 7xhv_B, 5sy7_B, 4zpk_B, 7xi3_B, 5v0l_B |
| Binding Motifs: | MA0603.1 dgTCACGTGh BMAL1_MOUSE.H10MO.C|M01024 kGrwCACGTGRCys MA0603.2 gTCACGTG |
| Publications: | Swanson H. I., Chan W. K., Bradfield C. A. DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins. J. Biol. Chem. 270:26292-26302 (1995). [Pubmed] |
| Related annotations: | PaperBLAST |
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