Transcription Factor
| Accessions: | Q91ZK4 (JASPAR 2024) |
| Names: | Diencephalon/mesencephalon homeobox protein 1, Diencephalon/mesencephalon-expressed brain homeobox gene 1 protein, DMBX1_MOUSE, Orthodenticle homolog 3, Paired-like homeobox protein DMBX1, Paired-type homeobox Atx |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q91ZK4 |
| Length: | 381 |
| Pfam Domains: | 72-128 Homeobox domain 355-373 OAR domain |
| Sequence: (in bold interface residues) | 1 MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIIL 60 61 EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK 120 121 NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKVEAPASDTQLETEQPPGLPSGDPPAELQ 180 181 LSLSEQSASESAPEDQLDREEDSRAEEPKAEKSPGSESKVPGCKRGSPKADSPGSLAITP 240 241 AAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLMHYSSFEVGGPAPAAAAAAAAA 300 301 VPYLGVNMAPLSSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPTGLAPASAALNSKTTSI 360 361 ENLRLRAKQHAASLGLDTLPN |
| Interface Residues: | 71, 72, 73, 74, 75, 113, 114, 116, 117, 120, 121, 124, 125, 128 |
| 3D-footprint Homologues: | 4j19_B, 1ig7_A, 6a8r_A, 3cmy_A, 2h1k_B, 1puf_A, 3d1n_M, 5zfz_A, 1fjl_B, 1nk2_P, 1zq3_P, 3lnq_A, 1jgg_B, 2lkx_A, 1au7_A, 6m3d_C, 2ld5_A, 7q3o_C, 6es3_K, 2hos_A, 1b72_A, 5zjt_E, 3a01_E, 7psx_B, 5hod_A, 5jlw_D, 3rkq_B, 4xrs_G, 2hdd_A, 4cyc_A, 2r5y_A, 1puf_B, 5flv_I, 3l1p_A, 1e3o_C, 1le8_A, 1o4x_A, 1du0_A, 4qtr_D |
| Binding Motifs: | MA0883.1 / PH0025.1 wdrwmmGGATTArkbww MA0883.2 rwmmGGATTA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.