Transcription Factor
Accessions: | CRX (HT-SELEX2 May2017) |
Names: | CRX, ENSG00000105392 |
Organisms: | Homo sapiens |
Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
Notes: | TF family: Homeodomain experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: Homeodomain experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4 |
Length: | 326 |
Pfam Domains: | 46-99 Homeobox domain |
Sequence: (in bold interface residues) | 1 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSPPLALDPPRRQRQERTVYTESQQKVL 60 61 EFYFQKDQYPNYDQRLNLAEMLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRG 120 121 ARAAPLVPVAAASFPGGPEFPQGRGSWISPQPGPWGVLPAAEPKIYSLPRTWGGPECGTQ 180 181 EGLKAVPAPGPGPIPAPIPGPAQIPGPVPGPAPNLGPMSGPLSVSIPGPIPAPISCPGPI 240 241 PDPVLGRTLMPGPGSLPTPAPGALWPQSPYASNLSPDTQLYPDFTKLLPLLDRFEESSLS 300 301 TTTSQYKEEDGFVDKNHSVPRSLLDL |
Interface Residues: | 45, 46, 47, 48, 49, 87, 88, 90, 91, 94, 95, 98, 99, 101, 102 |
3D-footprint Homologues: | 4j19_B, 3a01_E, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1fjl_B, 3d1n_M, 5zfz_A, 1ig7_A, 2lkx_A, 1nk2_P, 1zq3_P, 7q3o_C, 6es3_K, 2ld5_A, 1jgg_B, 7psx_B, 5hod_A, 3lnq_A, 2hdd_A, 1au7_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 6m3d_C, 5flv_I, 5zjt_E, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 4qtr_D, 3l1p_A, 1o4x_A, 1du0_A |
Binding Motifs: | CRX_2 cTAATCCs CRX_methyl_1 cTAATCCc |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.