Transcription Factor
Accessions: | T061535_1.02 (CISBP 1.02), Q03833 (JASPAR 2024) |
Names: | GIS1, T061535_1.02;, GIS1_YEAST |
Organisms: | Saccharomyces cerevisiae |
Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | experiment type:PBM, family:C2H2 ZF |
Length: | 894 |
Pfam Domains: | 13-46 jmjN domain 192-307 JmjC domain, hydroxylase 828-851 C2H2-type zinc finger 842-868 Zinc-finger double domain 857-878 C2H2-type zinc finger 857-878 Zinc finger, C2H2 type |
Sequence: (in bold interface residues) | 1 MEIKPVEVIDGVPVFKPSMMEFANFQYFIDEITKFGIENGIVKVIPPKEWLELLEGSPPA 60 61 ESLKTIQLDSPIQQQAKRWDKHENGVFSIENEYDNKSYNLTQWKNLAESLDSRISQGDFN 120 121 DKTLKENCRVDSQQDCYDLAQLQILESDFWKTIAFSKPFYAVDENSSIFPYDLTLWNLNN 180 181 LPDSINSSNRRLLTGQSKCIFPWHLDEQNKCSINYLHFGAPKQWYSIPSANTDQFLKILS 240 241 KEPSSNKENCPAFIRHQNIITSPDFLRKNNIKFNRVVQFQHEFIITFPYCMYSGFNYGYN 300 301 FGESIEFILDQQAVVRKQPLKCGCGNKKEERKSGPFSNLSYDSNESEQRGSITDNDNDLF 360 361 QKVRSFDELLNHSSQELQNLEDNKNPLFSNINMNRPQSSSLRSTTPNGVNQFLNMNQTTI 420 421 SRISSPLLSRMMDLSNIVEPTLDDPGSKFKRKVLTPQLPQMNIPSNSSNFGTPSLTNTNS 480 481 LLSNITATSTNPSTTTNGSQNHNNVNANGINTSAAASINNNISSTNNSANNSSSNNNVST 540 541 VPSSMMHSSTLNGTSGLGGDNDDNMLALSLATLANSATASPRLTLPPLSSPMNPNGHTSY 600 601 NGNMMNNNSGNGSNGSNSYSNGVTTAAATTTSAPHNLSIVSPNPTYSPNPLSLYLTNSKN 660 661 PLNSGLAPLSPSTSNIPFLKRNNVVTLNISREASKSPISSFVNDYRSPLGVSNPLMYSST 720 721 INDYSNGTGIRQNSNNINPLDAGPSFSPLHKKPKILNGNDNSNLDSNNFDYSFTGNKQES 780 781 NPSILNNNTNNNDNYRTSSMNNNGNNYQAHSSKFGENEVIMSDHGKIYICRECNRQFSSG 840 841 HHLTRHKKSVHSGEKPHSCPRCGKRFKRRDHVLQHLNKKIPCTQEMENTKLAES |
Interface Residues: | 802, 803, 805, 806, 808, 809, 811, 812, 813, 817, 818, 821, 837, 838, 839, 840, 841, 842, 843, 844, 845, 846, 849, 866, 867, 868, 869, 870, 871, 872, 873, 874, 875, 878, 893 |
3D-footprint Homologues: | 1tf3_A, 6ml4_A, 2kmk_A, 5yel_A, 7w1m_H, 8cuc_F, 7y3l_A, 3uk3_C, 7n5w_A, 1g2f_F, 5kl3_A, 2wbs_A, 1ubd_C, 5ei9_F, 2jpa_A, 1mey_C, 5und_A, 2drp_D, 8gn3_A, 1f2i_J, 5k5i_A, 6u9q_A, 7txc_E, 6blw_A, 5kkq_D, 2lt7_A, 6wmi_A, 4x9j_A, 2i13_A, 8ssq_A, 1llm_D, 5v3j_F, 4m9v_C, 2gli_A, 8h9h_G, 6e94_A, 7eyi_G, 7y3m_I, 1tf6_A, 7ysf_A, 6a57_A, 5yj3_D |
Binding Motifs: | M0506_1.02 wwwwAGGGGt MA0306.1 wCCCCTwww MA0306.2 CCCCTw |
Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.