Transcription Factor

Accessions: P02830 (JASPAR 2024)
Names: Homeobox protein Hox-1.1, Homeobox protein Hox-A7, Homeobox protein M6-12, HXA7_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 229
Pfam Domains: 130-186 Homeobox domain
Sequence:
(in bold interface residues)
1 MSSSYYVNALFSKYTAGASLFQNAEPTSCSFAPNSQRSGYGPGAGAFASTVPGLYNVNSP 60
61 LYQSPFASGYGLGADAYNLPCASYDQNIPGLCSDLAKGACDKADEGVLHGPAEASFRIYP 120
121 WMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNR 180
181 RMKWKKEHKDESQAPTAAPEDAVPSVSTAADKADEEEEEEEEEEEEEEE
Interface Residues: 128, 130, 131, 132, 133, 134, 171, 172, 174, 175, 178, 179, 182, 183, 186
3D-footprint Homologues: 1puf_A, 1fjl_B, 6a8r_A, 1ig7_A, 3cmy_A, 2h1k_B, 5zfz_A, 6m3d_C, 3d1n_M, 1zq3_P, 3lnq_A, 1jgg_B, 2lkx_A, 1nk2_P, 7q3o_C, 2ld5_A, 6es3_K, 5flv_I, 2hdd_A, 5zjt_E, 4cyc_A, 2r5y_A, 1puf_B, 7psx_B, 5hod_A, 2hos_A, 1b72_A, 3a01_E, 5jlw_D, 4xrs_G, 3rkq_B, 1e3o_C, 1le8_A, 7xrc_C, 3l1p_A, 4qtr_D, 1o4x_A, 1du0_A
Binding Motifs: PH0054.1 sgmrtTAATTAatwagc
PH0055.1 kkmkTAATTAmkggmm
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.