Transcription Factor
| Accessions: | Q8NDY6 (JASPAR 2024) |
| Names: | BHE23_HUMAN, bHLHb4, bHLHe23, Class B basic helix-loop-helix protein 4, Class E basic helix-loop-helix protein 23 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8NDY6 |
| Length: | 225 |
| Pfam Domains: | 102-152 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MAELKSLSGDAYLALSHGYAAAAAGLAYGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQ 60 61 AAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDAL 120 121 DGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNA 180 181 APLTPFGQATVCPFSAGAALGPCPDKCAAFSGTPSALCKHCHEKP |
| Interface Residues: | 102, 105, 106, 108, 109, 110, 112, 113 |
| 3D-footprint Homologues: | 2ypa_A, 6od3_F, 2ypa_B, 7d8t_A, 2ql2_A, 2ql2_D, 6g1l_A, 4h10_A, 8osl_P |
| Binding Motifs: | MA0817.1 aAmCATATGkTw MA0817.2 AmCATATGkT |
| Publications: | Atchley WR, Fitch WM. A natural classification of the basic helix-loop-helix class of transcription factors. Proc Natl Acad Sci U S A 94:5172-6 (1997). [Pubmed] |
| Related annotations: | PaperBLAST |
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